Mayo Clinic Proceedings - Current Understanding of Neurodegenerative Diseases Associated With the Protein Tau (August 1, 2017)

One of the premier peer-reviewed clinical journals in general and internal medicine, Mayo Clinic Proceedings is among the most widely read and highly cited scientific publications for physicians, with a circulation of approximately 125,000. Mayo Clinic Proceedings is published by Elsevier and sponsored by Mayo Clinic and the Mayo Foundation for Medical Education and Research. The mission of Mayo Clinic Proceedings is to promote the best interest of patients by advancing the knowledge and professionalism of the physician community. Since 2009 the Journal has offered CME credit for specific articles from both the Mayo Clinic for Concise Review for Clinicians and specially commissioned Symposia articles (comprehensive coverage on one topic).  

Participation in this activity consists of reviewing articles and responding to a short online test. It is estimated that this activity will take approximately one hour per article.  There is no charge for participating in this Journal CME activity.

To receive CME credit, please do the following:

  • Click Take Course
  • Complete quiz and evaluation (There is a required 80% pass rate in order to earn credit, with 1 retake allowed.)
  • Print your Record of Attendance

Questions?  cme@mayo.edu

Target Audience

The target audience for Mayo Clinic Proceedings is primarily internal medicine physicians and other clinicians who wish to advance their current knowledge of clinical medicine and who wish to stay abreast of advances in medical research.

Learning Objectives

On completion of this article, you should be able to: On completion of this article, you should be able to: (1) describe how tau biology and pathology relate to specific neurodegenerative diseases; (2) recognize the complex relationship between clinical diagnosis and underlying pathologies and predict pathology based on the presenting clinical syndrome; and (3) summarize the current status of the field in terms of the prion-like hypothesis of tau, the newly available tau positron emission tomography scan that can detect antemortem tau and what kinds of treatment approaches are currently being tried for the primary tauopathies.

Course summary
Available credit: 
  • 1.00 ABIM
  • 1.00 AMA PRA Category 1 Credit
Course opens: 
08/01/2017
Course expires: 
07/31/2019

DISCLOSURE SUMMARY:

No relevant financial relationships:

Planning Committee, Editorial Board Members and Staff
Thomas J. Beckman, M.D.
Timothy B. Curry, M.D., Ph.D.
William L. Lanier, Jr., M.D.
Terry Jopke
Eric L. Matteson, M.D.
Karl A. Nath, M.D.
S. Vincent Rajkumar, M.D.
Kimberly D. Sankey
Nicki Smith
A. Keith Stewart, M.D.
Margaret (Peg) Wentz
Christopher M. Wittich, M.D.

Relevant financial relationships: 

Editorial Board 
Michelle Mauermann, M.D. - Consultant - IONIS Pharmaceuticals, Honoraria - Continuum

Off-label drugs:  None.

AUTHORS DISCLOSURE SUMMARY: 

Author:  Keith A. Josephs, MD, MST, MSc

Affiliation: Professor of Neuroscience and Neurology, Mayo Clinic, Rochester, MN

Conflicts of Interest: The author reports no conflicts of interest. KAJ is funded by NIH grants R01 NS89757 (PI), R01 AG037491 (PI) and R21 NS94684 (PI).

Off-label drugs:  None.

Accreditation Statement:


In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Credit Statement(s):

AMA

Mayo Clinic College of Medicine and Science designates this Journal-based CME activity for a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity enables the participant to earn up to 1 MOC point in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points.

Other Healthcare Professionals

A certificate of attendance will be provided to other healthcare professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s), please go here.

Available Credit

  • 1.00 ABIM
  • 1.00 AMA PRA Category 1 Credit

Accreditation Period

Course opens: 
08/01/2017
Course expires: 
07/31/2019
Please login or create an account to take this course.