January 31 - February 5, 2027 - Hilton Waikoloa Village - Waikoloa, Hawaii

This course will be offered Live (in-person) only

The Mayo Clinic Interactive Surgery Symposium 2027 is designed to educate general surgeons on procedures seen in everyday practice. Difficult cases encountered in a smaller community practice rely on the best practices offered during the sessions. The symposium offers decision-making options that cover multiple aspects of surgical practice. Active audience participation with faculty is strongly encouraged during case presentations and faculty panel discussions. Surgical techniques are demonstrated through video presentations and audience response are used to enhance the interactive format. This symposium also features self-assessment credit toward Part 2 of the ABS MOC Program.

April 2-4, 2027 - Mayo Clinic - Phoenix, Arizona

This course is offered Live (in-person) only

Designed for experienced practitioners in operational aerospace medicine, the program emphasizes practical solutions to complex problems encountered during astronaut training, in-flight health maintenance, and post-mission rehabilitation. Participants will engage in confidential, small-group discussions on topics such as decompression sickness, hypoxia, radiation exposure, life-support systems, and emerging diagnostic and treatment methods for spaceflight environments.

February 26 - 27, 2027 - Mayo Clinic - Kinne Auditorium - Jacksonville, Florida

This course offers Live (in-person) and Livestream (virtual) attendance options

This course covers advanced topics in neuro-oncology, offering a review of advances in diagnosis and treatment of individuals with nervous system tumors. The course covers highlights from including the latest advances in neurosurgery, radiation oncology, neurology, and medical oncology, discussing novel therapeutic approaches that are transforming clinical practice with personalized treatments.

General Session: April 29 - May 1, 2027 - JW Marriott Tucson Starr Pass Resort & Spa - Tucson, Arizona

Special Feature: Pediatric Palliative Cases (Pre-Course Session Day) April 28, 2027. This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's Updates in Palliative Care is a multidisciplinary CME course designed to build and enhance your palliative care knowledge. Experts from Mayo Clinic provide clinically relevant pearls for palliative care providers and clinicians from primary care, hematology/oncology, hospital medicine, critical care, pediatrics, and related specialties. If you care for patients with serious illness and are looking to broaden your skills beyond the basics, this is the course for you.

April 8 - 10, 2027 - Integrated Education and Research Building - Phoenix, Arizona

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic Healthy Longevity Medicine is a comprehensive CME course designed to provide clinicians with clinically relevant knowledge in the emerging discipline of longevity medicine. The course delivers a structured curriculum focused on applying aging biology to patient care, with an emphasis on prevention, early risk detection, and healthspan extension. Participants will examine key biological mechanisms of aging—the hallmarks of aging—and explore how these processes contribute to functional decline, chronic disease risk, and potential targets for clinical intervention. The course covers a wide range of topics, including biomarkers of aging (biological age clocks), multidimensional assessment in geromedicine, lifestyle interventions, and emerging pharmacologic and regenerative therapies. Led by faculty from Mayo Clinic, alongside invited experts from national and international academic institutions, the course features a blend of didactic lectures and interactive case-based discussions. The course places emphasis on the critical appraisal of translational and clinical trials and the ethical considerations unique to the practice of geromedicine. Upon completion, participants will be equipped to thoughtfully integrate principles of geromedicine into their clinical care and contribute to the responsible advancement of longevity medicine.

May 6 - 8, 2027 - Omni Amelia Island - Fernandina Beach, Florida

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's 10th Annual Mayo Clinic Hematology/Oncology Case-Based Approaches to Patient Care for NPs, PAs, and Nurses 2027 focuses on the needs of advanced practice providers, physician assistants, nurse practitioners, and nurses regarding the care of patients with hematologic and oncologic malignancies. This case-based approach symposium highlights the day-to-day challenges in the care and management of patients, specifically addressing the needs of these clinical practitioners. This symposium highlights the complications and challenges that arise in caring for patients with various cancers.