Welcome to this mini-series on Inflammatory Bowel Disease, a dedicated podcast series exploring the complex world of IBD. Across seven insightful episodes, we break down essential topics—from diagnostic strategies to treatment innovations, and the unique experiences of special populations.

Join us as we explore these topics along with the guidance of Mayo Clinic’s leading experts:

  • The latest diagnosis and monitoring modalities
  • Advances in treatment strategies and clinical trials
  • Focused insights on pouchitis and microscopic colitis
  • The essentials of health maintenance for IBD patients
  • The complexities of IBD management in special populations
  • And the clinical considerations of IBD during pregnancy.

This series brings clarity, expertise, and empathy to some of IBD’s most pressing clinical conversations.

Mayo Clinic Gastroenterology Division:
X: @MayoClinicGIHep
Facebook:  Mayo Clinic Gastroenterology and Hepatology | Rochester MN | Facebook

Listening is free and no CME Credit is available for this series.  
Mayo Clinic Talks is a podcast series targeted to the primary care clinician community. To listen to additional episodes with CME credit available, visit Mayo Clinic Talks Season 3

Listen on your favorite podcast app below.

               


Guest: 


Sunanda V. Kane, M.D.

Inflammatory Bowel Disease Series: Inflammatory Bowel Disease (IBD) and Pregnancy

July 22, 2025

Host: Darryl S. Chutka, M.D.

Most people who develop inflammatory bowel disease are diagnosed before the age of 30. In women, this often occurs during the middle of their reproductive years. Some with inflammatory bowel disease choose to avoid pregnancy, usually due to misconceptions about pregnancy risks. Yet if properly managed, women can experience a normal, uneventful pregnancy and deliver a healthy child.  What effect does inflammatory bowel disease have on fertility? Do patients have a greater chance of a normal pregnancy if the bowel disease is in remission? How can patients minimize the risk of inflammatory bowel disease flares during pregnancy and are the pharmacologic therapies commonly used to treat inflammatory bowel disease safe to use during pregnancy? These are some of the questions I’ll ask my guest, Sunanda V. Kane, M.D., from the Division of Gastroenterology and Hepatology at the Mayo Clinic 

Guests:


Amanda M. Johnson, M.D.


Victor G. Chedid, M.D., M.S.

Inflammatory Bowel Disease Series: Inflammatory Bowel Disease in Special Populations: The Elderly, Obese and LGBTQ Patient

July 17, 2025

Host: Darryl S. Chutka, M.D.

This podcast continues our series on inflammatory bowel disease. The topic is important and timely: “Inflammatory Bowel Disease in Special Populations: The Elderly, the Obese and the LGBTQ Patient.” It’s critical that we broaden our perspective in addressing the unique challenges faced by these often-unrecognized population groups. How common is the presentation of inflammatory bowel disease in those over 65? How does age affect the treatments commonly used? Does obesity alter the disease presentation or activity and what are some of the unique challenges our LGBTQ patients face with inflammatory bowel disease? These are just some of the questions I’ll be asking my guests, Amanda M. Johnson, M.D., and Victor G. Chedid, M.D., M.S., both gastroenterologists at the Mayo Clinic.


Guest: Konstantinos A. Papadakis, M.D.

Inflammatory Bowel Disease Series: Health Maintenance in Inflammatory Bowel Disease (IBD)

July 15, 2025

Host: Darryl S. Chutka, M.D.

Due to the complexity and new pharmacologic options for the management of inflammatory bowel disease, patients often have their care provided by a gastroenterologist. They may not see their primary care provider as often as in the past and some of their preventive health maintenance may not get performed. Are patients receiving primarily specialty care still receiving good health maintenance?  Are we aware that patients with inflammatory bowel disease have some unique needs regarding their preventive health maintenance and some of the recommendations are different than the general population? These are questions I’ll be asking my guest, gastroenterologist Konstantinos A. Papadakis, M.D., from the Mayo Clinic.

Guests: 


Darrell S. Pardi, M.D.


Laura E. Raffals, M.D.

Inflammatory Bowel Disease Series: Pouchitis

July 10, 2025

Host: Darryl S. Chutka, M.D.

Pouchitis is a relatively common complication in patients who have ulcerative colitis and have had a proctocolectomy with an ileal pouch-anal anastomosis. It represents inflammation of the ileal pouch and symptoms may include increased stool frequency, cramps, fecal urgency and occasionally bloody stools. The diagnosis is usually suspected from clinical symptoms and confirmed with endoscopy. Are there risk factors for the development of pouchitis? Is an endoscopy necessary for a diagnosis? How should patients be treated and how effective is treatment? These are some of the questions I’ll be asking my guests, Darrell S. Pardi, M.D., and Laura E. Raffals, M.D., both gastroenterologists at the Mayo Clinic. 

Guests: 


Darrell S. Pardi, M.D.


Laura E. Raffals, M.D.

Inflammatory Bowel Disease Series: Microscopic Colitis

July 8, 2025

Host: Darryl S. Chutka, M.D.

Microscopic colitis is one of the lesser-known members of the inflammatory bowel disease family. Symptoms include chronic, frequent diarrhea and fecal urgency. It’s usually suspected from the patient’s clinical symptoms and diagnosis is established by colonoscopy with biopsy. Biopsy is necessary as the colonic mucosa appears normal at endoscopy. A specific cause isn’t known but it can be associated with several medications. Although it’s not typically a life-threatening condition, it can lead to weight loss and potentially dehydration. How does microscopic colitis differ from ulcerative colitis or Crohn’s Disease? Who’s at risk of developing it? Since these patients usually present to primary care providers, when should we suspect it? How is it managed, and can it be cured?  These are some of the questions I’ll be asking my guests, Darrell S. Pardi, M.D., and Laura E. Raffals, M.D., both gastroenterologists at the Mayo Clinic. 


Guest: Edward V. Loftus JR, M.D.

Inflammatory Bowel Disease Series: Inflammatory Bowel Disease (IBD) and its Treatment

July 3, 2025

Host: Darryl S. Chutka, M.D.

Inflammatory Bowel Disease is somewhat of an umbrella term for a group of chronic inflammatory conditions of the GI tract. The most common types include ulcerative colitis and Crohn’s Disease. While there are similarities between the two, there are also differences. For many individuals with inflammatory bowel disease, it’s only a mild illness. Unfortunately for some, it can lead to severe disability and potentially life-threatening complications. What are the similarities and differences between ulcerative colitis and Crohn’s? When should we suspect a patient has an inflammatory bowel disease? What’s the best way to establish a diagnosis and finally, what treatment options do we have? These are just some of the questions I’ll be asking my guest, Edward V. Loftus JR, M.D., from the Division of Gastroenterology and Hepatology at the Mayo Clinic as we discuss “Inflammatory Bowel Disease and Its Treatment”.

Guests: 


David H. Bruining, M.D.,


Nayantara Coelho-Prabhu, M.B.B.S.

Inflammatory Bowel Disease Series: Diagnosing Inflammatory Bowel Disease (IBD) and Monitoring Modalities

July 1, 2025

Host: Darryl S. Chutka, M.D.

An early diagnosis of inflammatory bowel disease is important in preventing long-term complications. Prompt treatment can improve quality of life, reduce the likelihood of hospitalizations, and help maintain remissions. However, establishing a diagnosis is often challenging due to the nonspecific and fluctuating nature of symptoms. Inflammatory bowel disease can also mimic other GI conditions. In addition, diagnostic confirmation usually requires a combination of blood tests, imaging, endoscopy, and histological analysis, making the process both time consuming and complex.  The topic for today's podcast is “Diagnosing Inflammatory Bowel Disease and Monitoring Modalities” and my guests are David H. Bruining, M.D., and Nayantara Coelho-Prabhu, M.B.B.S., from the Division of Gastroenterology and Hepatology at the Rochester campus of the Mayo Clinic.