Mayo Clinic Talks is a weekly podcast show for healthcare professionals in primary care and all specialties. Podcasting offers succinct, relevant, accessible, and practical medical information which is useful for the primary care professional. The episodes in this course reflect commonly seen health problems in a primary care practice and other topics of interest. Mayo Clinic professionals from numerous medical specialties join as podcast guests covering an extremely wide variety of pertinent medical topics. Each podcast is succinct, kept to 20-30 minutes, allowing the busy healthcare professional to obtain useful information efficiently.  Listening is free and no CME Credit is available for the episodes.

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Rx for Weight Loss: A Closer Look Series "Importance of Lifestyle Changes with Use of GLP-1 Medications"

January 13, 2026

Using GLP-1 medication for weight loss has become very popular with our patients. In the recent past, this has produced a shortage of these medications available, and those taking them for management of diabetes have found them difficult to obtain. Although in most cases, they are quite successful in producing substantial weight loss, many have regained weight after the medication was discontinued. How much weight can patients expect to lose with these medications? When should these medications be stopped, or should they? Are there strategies that have shown benefit to help patients maintain the weight they lose once the medication is discontinued? This podcast is the second of three on using the GLP-1 medications for weight loss and we’ll discuss “The Importance of Lifestyle Changes with the Use of GLP-1 Medications for Weight Loss”. My guest is Dr. Tamim Rajjo, a physician trained in Preventive Medicine and Obesity Medicine from the Mayo Clinic. 

Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development 

Rx for Weight Loss: A Closer Look Series “Who is a Candidate for a GLP-1 Medication?”

January 8, 2026

Using GLP-1 medications for weight loss has become extremely popular. Is this the latest fad in losing weight, or will these medications completely change our approach to managing obesity? They do appear to be very effective in promoting substantial weight loss. What is the history of these medications? Are there differences in the various GLP-1 medications available? What are the potential adverse effects of this drug class? This podcast is the first in a series of three on the GLP-1 medications prescribed for weight loss. The topic for this podcast is “Who Is a candidate for a GLP-1 Medication?” and my guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology and Metabolism at the Mayo Clinic.

Check out the series!
Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development

The Risks and Benefits of Alcohol

WELCOME TO SEASON 6 OF THE MAYO CLINIC TALKS PODCAST!
January 6, 2026

Alcohol can offer a variety of social and potential health benefits when consumed in moderation. However, alcohol is also associated with a variety of health risks, including addiction, increased likelihood of accidents, impaired judgment, cardiovascular problems, hepatic disease and even malignancy. Other than the social benefits, are there true health benefits of alcohol? Is there an amount of alcohol that’s considered safe? How can we as primary care clinicians convey the health risks of alcohol to our patients? The topic for this podcast is the “Risks and Benefits of Alcohol” and these are some of the questions I’ll be asking my guest, Warren G. Thompson, M.D., an internist and preventive medicine specialist at the Mayo Clinic.