Pharmacy Grand Rounds

Better Cef than Sorry: Beta-Lactam Monitoring in the ICU

• ACPE Universal Activity Number (UAN): JA0000238-0000-20-028-L01-P
• Session Type: Knowledge-based
• CE Credits: A maximum of 0.75 contact hour (0.075 CEU) for the following: 
  • AAPA Category 1 CME Credits
  • ACPE
  • AMA PRA Category 1 Credits™
  • ANCC

• Session Fee: Free for Mayo Clinic staff

SESSION LOCATIONS

Live Session: (11:00am - 11:45am CST)
MN-RO-AL-08-459-Walters Hall  - For Presenter Only

Until future notice, learners must watch Pharmacy Grand Rounds live via the web by going to the Video Exchange and selecting “Pharmacy Grand Rounds” in the “Steaming Now” section.

Participants may attend by viewing: Live Webcast
Video Recording - access two weeks after session date

COURSE DESCRIPTION

Since their discovery and subsequent commercialization in the 1940s, beta-lactam antibiotics have become the cornerstone of pharmacotherapy for infectious diseases. Of the 4 million ICU admissions in the United States annually, a large portion receive antibiotics, including beta-lactams, during their hospitalization. The pharmacokinetic alterations of critical illness have been well-described and the implications these alterations have on the efficacy and toxicity of beta-lactam antibiotics is of significant concern. The therapeutic drug monitoring of beta-lactams has emerged as a potential tool to individualize regimens for these agents in ICU patients. This presentation aims to summarize the literature describing the role of beta-lactam monitoring in the ICU and detail the practical considerations of its routine practice.

At the conclusion of this knowledge-based CE session, participants should be able to:

1. Describe the pharmacokinetic alterations of critical illness and the implications for beta-lactam optimization
2. Recognize the potential role of beta-lactam therapeutic monitoring in predicting drug effectiveness
3. Identify the potential role of beta-lactam therapeutic monitoring in recognizing drug toxicity

Session Announcement

Session Slides

FACULTY INFORMATION

Andrew J. Webb, PharmD
PGY1 Pharmacy Resident
Mayo Clinic Hospital - Rochester, MN

Andy received his Doctor of Pharmacy degree from the University of Rhode Island. He is a current PGY1 Pharmacy Resident at Mayo Clinic Hospital-Rochester and has practice interests are in neurology, critical care, and infectious diseases.

DISCLOSURE STATEMENTS

As a provider accredited by Joint Accreditation Interprofessional Continuing Education, Mayo Clinic College of Medicine and Science (Mayo Clinic School of CPD) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course Director(s), Planning Committee Members, Faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of these relevant financial relationships will be published in activity materials so those participants in the activity may formulate their own judgments regarding the presentation.

Listed below are individuals with control of the content of this program:

The faculty report the following relationships:

• Andrew J. Webb, PharmD
  • Declares no financial relationships pertinent to this session
  • Declares off-label use of devices and medications will be not discussed during this presentation

Course Director and Planning Committee Members declare no relevant financial relationship(s) pertinent to this session.  Members include:

• Brenda Amaris
• Mary Ellen Cordes, MS, APRN, CNC, NE-BC
• Michael Huckabee, MPAS, PA-C, PhD
• Wayne (Nick) Nicholson, MD, PharmD, BCPS
• Garrett Schramm, PharmD, BCPS
• Lee Skrupky, PharmD, BCPS