PRESENTATION TITLE
Where have we gone wrong with Glioblastoma?
PRESENTER(S)
Jann N. Sarkaria, M.D.
Professor of Radiation Oncology, Consultant, Radiation Oncology, Mayo Clinic, Rochester, Minnesota

PRESENTER BIO

Jann N. Sarkaria, M.D., is a consultant in the Department of Radiation Oncology at Mayo Clinic in Rochester, Minnesota. Dr. Sarkaria joined the staff of Mayo Clinic in 1997 and holds the academic rank of professor of radiation oncology, Mayo Clinic College of Medicine and Science.

Dr. Sarkaria earned his B.S. in biology and chemistry from the University of California at Irvine and his M.D. at the University of California Los Angeles. He completed an internship at the University of Hawaii, followed by a radiation oncology residency at the University of Wisconsin. During residency, he was awarded fellowships from the American Society of Therapeutic Radiology and Oncology and from the National Institutes of Health to support a research fellowship in radiobiology at the Institute for Cancer Research in Sutton, England. He continued his training through a postdoctoral research fellowship in the Department of Oncology at Mayo Clinic.

Dr. Sarkaria’s translational neuro-oncology laboratory is focused on developing novel therapeutic strategies for people with glioblastoma (GBM) and brain metastases. Global interests in the lab include understanding the basis of resistance to chemotherapy and radiation, identifying methods to overcome therapy resistance, integration of novel signal transduction inhibitors into conventional therapies for newly diagnosed or recurrent GBM, and use of next-generation sequencing and proteomics to guide individualized therapy for patients with GBM. His research is funded by the National Institute of Neurological Disorders and Stroke and the National Cancer Institute.

In addition to his clinical and research activities, Dr. Sarkaria is active in education, which includes serving as course chair and instructor for Radiobiology for radiation oncology residents. He holds full faculty privileges in the Biochemistry and Molecular Biology Program in Mayo Clinic Graduate School of Biomedical Sciences.

VIEWING LOCATIONS
Zoom Registration Link

LEARNING OBJECTIVES

• Review use of patient derived GBM models in clinical translation.
• Describe integration of pharmacokinetics, pharmacodynamics, and efficacy evaluations across animal models.
• Examine benchmarks of an effective therapy in animal models.

ATTENDANCE / CREDIT
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TRANSCRIPT
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