Neurology Grand Rounds Conference (26R00584)

Microsoft Zoom
Join from PC, Mac, iPad, or Android:
https://mc-meet.zoom.us/j/99160135636?pwd=BVJvfVlrveGHV4xuHvw7wtW6jIU61J.1
Passcode:246189

Faculty Presenting - Sam Nath, M.D., Ph.D.
Title: "Making Waves: Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle disease"

Learning Objectives
Upon conclusion of this activity, participants will be able to:

• Describe the clinical features of Rippling Muscle Disease (RMD) and distinguish between hereditary and immune-mediated forms, including the role of cavin-4 autoantibodies as a biomarker of immune-mediated RMD
• Explain how alterations in calcium-handling proteins may disrupt muscle relaxation dynamics and contribute to the pathophysiology of rippling in immune-mediated RMD.
• Define the transcriptomic findings from muscle biopsies of iRMD patients, including compensatory upregulation of cavin-4 expression and overlap in immune pathways with dermatomyositis, particularly IL-6 signaling
• Interpret current gaps in the understanding of skeletal muscle pathophysiology and potential avenues for future investigation in immune-mediated myopathies.

Presenter: Christina Alexandres, M.D.

Title: " Revisiting REM Sleep Behavior Disorder"

Learning objectives:

                                           Upon conclusion of this activity, participants will be able to:

• Assess the history of REM Sleep Behavior Disorder (RBD) and its association with alpha-synucleinopathy
• Identify limitations of prior research in clinical practice and need for research to understand the demographics of RBD
• Define the significance of the association between RBD and neurodegenerative disorders
• Assess goals of ongoing research projects on RBD and implications for future clinical practice

   

Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Credit Statement(s):

AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 0.75 AMA PRA Category 1 Credits^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
AAPA
Mayo Clinic College of Medicine and Science has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.75 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 0.75 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity. 

Faculty:

Sherri Braksick, M.D.
Heather Clark, Ph.D.
Lyell Jones, M.D.
Janice Klaassen, M.A., R.N.
Eugene Scharf, M.D.
Stephanie Steel, M.D.
Derek Stitt, M.D.
Forrest Sturgill, M.D.
Adrienne Wyant, P.A.-C.
Bryan Hunt (Coordinator)
Nicole Meyer (Coordinator)
Tracy Skogerbo (Coordinator)

ATTENDANCE / CREDIT
Text the session code (provided only at the session) to 507-200-3010 within 48 hours of the live presentation to record attendance. All learners are encouraged to text attendance regardless of credit needs. This number is only used for receiving text messages related to tracking attendance. Additional tasks to obtain credit may be required based on the specific activity requirements and will be announced accordingly. Swiping your badge will not provide credit; that process is only applicable to meet GME requirements for Residents & Fellows.

TRANSCRIPT
Any credit or attendance awarded from this session will appear on your Transcript.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.