A Systematic Approach to Medically Unexplained Symptoms 2025
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Course Directors - Arya B. Mohabbat, MD, Michael R. Mueller, MD, Elizabeth C. Wight, MD
August 13 - 16, 2025 - Four Seasons Hotel Chicago - Chicago, Illinois (All scheduled times noted are in the Central time zone)
This course will provide evidence-based strategies to address frequently encountered medically unexplained conditions. We will begin with a thorough discussion of the pathophysiological process of central sensitization; this will be followed by lectures focusing on specific medically unexplained conditions and symptoms. Each topic will utilize didactic sessions, case vignettes, clinical pearls, helpful tips, and formal Q/A sessions. Breakfast and Break with the experts will also be provided to allow for additional discussion. The conference also includes an optional, separately purchased afternoon workshop focusing on burnout, wellness, resilience, and mindfulness.
This course offers Live (in-person) and Livestream* (virtual) attendance options
*To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery and post-course recordings will not be available. Livestream will be presented as voiceover PowerPoint only, no live camera feed on the presenter.
Wednesday, August 13, 2025; 7:15 am - 12:45 pm
Optional Workshop; 12:45 - 5:05 pm
Thursday, August 14, 2025; 7:00 am - 1:35 pm
Friday, August 15, 2025; 7:00 am - 1:05 pm
Saturday, August 16, 2025; 7:00 am - 1:35 pm
Registration Fees | |
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General Session (Available In-Person and Livestream) | |
MD, DO, PhD | $995 |
Nurse Practitioner, Physician Assistant, Nurse, Resident, Fellow, Allied Health Professional, Retiree | $925 |
Optional Workshop (Available In-Person and Livestream) | |
Burnout, Well-Being, and Resiliency: Tips to Care for You and Your Patients | $225 |
Target Audience
This course is intended for general internists, internal medicine subspecialists, family medicine physicians, physician assistants, nurse practitioners, and other primary healthcare professionals who practice in or have a special interest in treating medically complex patients.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Define the pathophysiological process of central sensitization
- Highlight the relationship between central sensitization and medically unexplained symptoms
- Identify treatment strategies for fibromyalgia
- Identify treatment strategies for chronic fatigue syndrome
- Highlight the clinical approach to managing various chronic gastrointestinal symptoms
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
Printable version of A Systematic Approach to Medically Unexplained Symptoms 2025 program.
A Systematic Approach to Medically Unexplained Symptoms 2025 |
Four Seasons Hotel Chicago, IL |
August 13 – 16, 2025 |
Note: Times are listed in Central time To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery and post-course recordings will not be available. |
WEDNESDAY, AUGUST 13, 2025 – General Session
7:15 – 7:50 AM | Registration and Breakfast |
7:50 – 8:00 AM | Introductions and Announcements |
8:00 – 8:40 AM | Central Sensitization: A Pathophysiological Review |
8:50 – 9:35 AM | Fibromyalgia |
9:45 – 10:30 AM | Chest Pain and Palpitations |
10:40 – 11:10 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom. |
11:10 – 11:50 AM | Chronic Dizziness |
12:00 – 12:35 PM | Approach to Breast Pain |
12:45 PM | Adjourn General Session |
*Burnout, Well-Being, and Resiliency: Tips to Care for You and Your Patients
(Optional, separate registration)
12:45 – 1:00 PM | Pick Up Lunches - For in-person workshop attendees only. |
1:00 – 1:05 PM | Welcome |
1:05 – 1:55 PM | Lunch Talk: Tackling Burnout and Related Syndromes in the Healthcare Team |
1:55 – 2:35 PM | Practical Aspects of Leading a Healthy Lifestyle |
2:35 – 3:20 PM | Wellness Coaching for You and Your Patients |
3:20 – 3:35 PM | BREAK |
3:35 – 4:25 PM | A SMART Approach to Resiliency |
4:25 – 5:05 PM | Experiential Mindfulness |
5:05 PM | Adjourn Workshop |
THURSDAY, AUGUST 14, 2025 – General Session
7:00 – 7:55 AM | Breakfast with the Experts Livestream audience will access Breakout rooms within Zoom. |
7:55 – 8:00 AM | Introductions and Announcements |
8:00 – 8:45 AM | Chronic Fatigue Syndrome |
8:55 – 9:40 AM | Approach to Chronic Headaches |
9:50 – 10:35 AM | Long COVID Syndrome |
10:45– 11:15 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom. |
11:15 AM – 12:00 PM | Approach to Chronic Gastrointestinal Symptoms |
12:10 – 12:40 PM | Approach to the Patient with “Adrenal Fatigue” |
12:50 – 1:25 PM | Approach to Insomnia |
1:35 PM | Adjourn General Session |
FRIDAY, AUGUST 15, 2025 – General Session
7:00 – 7:55 AM | Breakfast with the Experts Livestream audience will access Breakout rooms within Zoom. |
7:55 – 8:00 AM | Introductions and Announcements |
8:00 – 8:45 AM | Importance of Patient Stories and Medically Unexplained Symptoms |
8:55 – 9:40 AM | Postural Tachycardia Syndrome |
9:50 – 10:35 AM | The Rheumatologist Will See You Now |
10:45– 11:15 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom. |
11:15 AM – 12:00 PM | Women's Health in Medically Unexplained Symptoms |
12:10 – 12:55 PM | Controversies in Allergy-Immunology |
1:05 PM | Adjourn General Session |
SATURDAY, AUGUST 16, 2024 – General Session
7:00 – 7:55 AM | Breakfast with the Experts Livestream audience will access Breakout rooms within Zoom. |
7:55 – 8:00 AM | Introductions and Announcements |
8:00 – 8:45 AM | Evaluation of Thyroid Hormones: Myths, Truths, and In-Between |
8:55 – 9:40 AM | Unexplained Chronic Cough |
9:50 – 10:35 AM | Psychiatry in Medically Unexplained Symptoms |
10:45– 11:15 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom. |
11:15 AM – 12:00 PM | Approach to Pelvic Pain and Dysfunction |
12:10 – 12:55 PM | Approach to Rehabilitation |
1:05 PM | Adjourn Conference - Thank you for joining us! |
Guest rooms have been reserved for attendees and their guests with special course rates at Four Seasons Hotel Chicago. In order to receive the special rate, reservations must be made before the room block is filled or before the expiration date of Monday, July 21, 2025, whichever comes first. Reservations will be taken following this date based on space and rate availability.
Online reservation link coming soon!
Phone: 312-280-8400 - Reference Mayo Clinic 2025
Four Seasons Hotel Chicago Room Block Details
- King Bedded Room $375 per night (plus city taxes 4.5%, state tax 11.9%, county tax 1%)
- A maximum of three (3) adults will be allowed per room. An additional charge of $40.00 per night will be assessed for a third adult (18 years or older)
- Waived fee for rollaway bed
- Complimentary basic wireless internet in guestrooms
- Complimentary access to the Swimming Pool and 24-hour Fitness Center
Check in: 3:00 pm
Check out: 12:00 pm
Spa & Wellness Services
Services and Amenities
Parking and Transportation
Valet parking for $77 per night.
Self-parking is available in the 900 North Michigan building for $54 per night.
Airports
O'Hare International Airport (ORD) approximately 18 miles
Midway Airport (MDW) approximately 13 miles
All travel and lodging expenses are the sole responsibility of the individual registrant.
Course Directors | ||
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Arya B. Mohabbat, MD | Michael R. Mueller, MD | Elizabeth C. Wight, MD Assistant Professor of Medicine Division of General Internal Medicine |
Faculty | ||
Chris A. Aakre, MD | Amindra S. Arora, MB, BChir Professor of Medicine Division of Gastroenterology & Hepatology | Erica Bellamkonda, MD |
Larry R. Bergstrom, MD Assistant Professor of Medicine Division of General Internal Medicine | Greg P. Couser, MD, MPH Assistant Professor of Psychiatry Assistant Professor of Medicine Division of Preventative, Occupational, and Aerospace Medicine | Michael W. Cullen, MD Associate Professor of Medicine Division of Cardiovascular Diseases |
Rohit D. Divekar, MBBS, PhD Assistant Professor of Medicine Division of Allergic Diseases | Daniel V. Dudenkov, MD Assistant Professor of Medicine Division of General Internal Medicine | Jamie L. Friend, NBC-HWC Lead Wellness Coach Division of General Internal Medicine |
Debbie L. Fuehrer, MA, LPCC Assistant Professor of Medicine Division of General Internal Medicine | Stephanie L. Grach, MD Assistant Professor of Medicine Division of General Internal Medicine | Isabel C. Green, MD Associate Professor of Obstetrics & Gynecology Department of Obstetrics & Gynecology |
Donald D. Hensrud, MD, MS Associate Professor of Preventive Medicine Associate Professor of Nutrition Division of General Internal Medicine | Vivek N. Iyer, MD, MPH Associate Professor of Medicine Division of Pulmonary & Critical Care Medicine | Mithri Junna, MD. Assistant Professor of Neurology Department of Neurology |
Ashima Makol, MBBS Associate Professor of Medicine Division of Rheumatology | Jean Marie McGowan, MD Instructor in Medicine Division of General Internal Medicine | LaSonya T. Natividad, ARNP, CNP, MSN** Instructor in Medicine Division of General Internal Medicine |
Neena Natt, MD Associate Professor of Medicine Division of Endocrinology, Diabetes & Metabolism | Sandhya Pruthi, MD* Professor of Medicine Division of General Internal Medicine | Mabel Ryder, MD Associate Professor of Medicine Division of Endocrinology, Diabetes & Metabolism |
Jeffrey P. Staab, MD, MS Professor of Psychology Department of Psychiatry & Psychology | Jason H. Szostek, MD Assistant Professor of Medicine Division of General Internal Medicine | Iris Wang, MD Assistant Professor of Medicine Division of Gastroenterology & Hepatology |
Elizabeth W. Westby, MD Assistant Professor of Family Medicine Department of Family Medicine | Nathan P. Young, DO Assistant Professor of Neurology Department of Neurology |
*Planning team member, AAFP diplomate
**Planning team member, ANCC diplomate
CME Program Manager- Deb Blomberg, MBA
CME Education Specialist- Sheila Terrill
RSTGIMCME@mayo.edu for questions or support
Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 27.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Credit allocation:
Wednesday 8/13/25 General Session: 4.75
Wednesday 8/13/25 Optional Workshop: 3.75
Thursday 8/14/25 General Session: 6.50
Friday 8/15/25 General Session: 6.00
Saturday 8/16/25 General Session: 6.00
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 27.00 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
Other Healthcare Professionals:
A record of attendance will be provided to all registrants for requesting credits in accordance with state nursing boards, specialty societies or other professional associations.
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Available Credit
- 27.00 AMA PRA Category 1 Credit™
- 27.00 ANCC
- 27.00 Attendance
Notify me when A Systematic Approach to Medically Unexplained Symptoms 2025 registration opens
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To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Equity, Diversity and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which individual differences are valued, allowing all to achieve their fullest potential.
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