March 3-6, 2027 - Hyatt Regency Maui - Lahaina, Maui, Hawaii

This course offers Live (in-person) and Livestream (virtual) attendance options

This Mayo Clinic and Kaiser Permanente collaboration offers a comprehensive family medicine update course designed for practicing primary care and family medicine providers. This course highlights the latest recommendations involving medical specialties important to the primary care setting that can be applied immediately into practice. For those attending in person, the use of lectures, panel, and roundtable discussions offers attendees opportunities to interact with faculty.

April 2-4, 2027 - Mayo Clinic - Phoenix, Arizona

This course is offered Live (in-person) only

Designed for experienced practitioners in operational aerospace medicine, the program emphasizes practical solutions to complex problems encountered during astronaut training, in-flight health maintenance, and post-mission rehabilitation. Participants will engage in confidential, small-group discussions on topics such as decompression sickness, hypoxia, radiation exposure, life-support systems, and emerging diagnostic and treatment methods for spaceflight environments.

April 8 - 10, 2027 - Integrated Education and Research Building - Phoenix, Arizona

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic Healthy Longevity Medicine is a comprehensive CME course designed to provide clinicians with clinically relevant knowledge in the emerging discipline of longevity medicine. The course delivers a structured curriculum focused on applying aging biology to patient care, with an emphasis on prevention, early risk detection, and healthspan extension. Participants will examine key biological mechanisms of aging—the hallmarks of aging—and explore how these processes contribute to functional decline, chronic disease risk, and potential targets for clinical intervention. The course covers a wide range of topics, including biomarkers of aging (biological age clocks), multidimensional assessment in geromedicine, lifestyle interventions, and emerging pharmacologic and regenerative therapies. Led by faculty from Mayo Clinic, alongside invited experts from national and international academic institutions, the course features a blend of didactic lectures and interactive case-based discussions. The course places emphasis on the critical appraisal of translational and clinical trials and the ethical considerations unique to the practice of geromedicine. Upon completion, participants will be equipped to thoughtfully integrate principles of geromedicine into their clinical care and contribute to the responsible advancement of longevity medicine.

General Session: April 29 - May 1, 2027 - JW Marriott Tucson Starr Pass Resort & Spa - Tucson, Arizona

Special Feature: Pediatric Palliative Cases (Pre-Course Session Day) April 28, 2027. This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's Updates in Palliative Care is a multidisciplinary CME course designed to build and enhance your palliative care knowledge. Experts from Mayo Clinic provide clinically relevant pearls for palliative care providers and clinicians from primary care, hematology/oncology, hospital medicine, critical care, pediatrics, and related specialties. If you care for patients with serious illness and are looking to broaden your skills beyond the basics, this is the course for you.

May 6 - 8, 2027 - Omni Amelia Island - Fernandina Beach, Florida

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's 10th Annual Mayo Clinic Hematology/Oncology Case-Based Approaches to Patient Care for NPs, PAs, and Nurses 2027 focuses on the needs of advanced practice providers, physician assistants, nurse practitioners, and nurses regarding the care of patients with hematologic and oncologic malignancies. This case-based approach symposium highlights the day-to-day challenges in the care and management of patients, specifically addressing the needs of these clinical practitioners. This symposium highlights the complications and challenges that arise in caring for patients with various cancers.

May 26-29, 2027 - Ritz Carlton – Orlando, Florida

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's Neuro and Intensive Care: Review, Workshops and Controversies 2027 is a CME course designed for medical professionals who care for patients with neurological/neurosurgical emergencies, acute stroke and brain hemorrhage, acute brain injury, coma and disorders that require hospital, emergency department, and intensive care unit evaluation and management. The course provides a mixture of didactic, case-based and evidence-based guideline review and workshops. Pharmacotherapy and ICU EEG workshops utilize audience participation in on-screen quizzes and share protocols regarding osmotherapy for raised intracranial pressure and antiepileptic drug therapy.