Mayo Clinic Healthy Longevity Medicine: Translating Geroscience into Clinical Practice
This course offers Live (in-person) and Livestream (virtual) attendance options

Course Directors: Sara L. Bonnes, M.D., M.S., Atul Jain, M.D., M.S., and Doina Kulick, M.D.
April 8 - 10, 2027 - Integrated Education and Research Building - Phoenix, Arizona
Mayo Clinic Healthy Longevity Medicine: Translating Geroscience into Clinical Practice is a comprehensive CME course designed to provide clinicians with clinically relevant knowledge in the emerging discipline of healthy longevity medicine (geromedicine). The course delivers a structured curriculum focused on applying aging biology (geroscience) to patient care, with an emphasis on prevention, early risk detection, and healthspan extension. Participants examine key biological mechanisms of aging—the hallmarks of aging—and explore how these processes contribute to functional decline, chronic disease risk, and potential targets for clinical intervention. The course covers a wide range of topics, including biomarkers of aging (biological age clocks), multidimensional assessment in geromedicine, lifestyle interventions, and emerging pharmacologic and regenerative therapies. Led by faculty from Mayo Clinic, alongside invited experts from national and international academic institutions, the course features a blend of didactic lectures and interactive case-based discussions. The course places emphasis on the critical appraisal of translational and clinical trials and the ethical considerations unique to the practice of geromedicine. Upon completion, participants are equipped to thoughtfully integrate principles of geromedicine into their clinical care and contribute to the responsible advancement of healthy longevity medicine.
Target Audience
This course is intended for general internists, hospitalists, family practitioners, and allied health staff interested in healthy longevity medicine (geromedicine).
Learning Objectives
Upon completion of this activity, participants should be able to:
- Define the emerging field of geromedicine (longevity medicine).
- Describe the key mechanisms that drive the biology of aging.
- Recognize the role of biomarkers of aging in geromedicine (longevity medicine).
- Describe how precision medicine tools are incorporated into healthspan assessments (e.g. analyzing genomics, biomarkers, and wearable data) for health optimization.
- Identify the major imaging techniques used in longevity medicine.
- Examine the evidence-based clinical interventions in healthy longevity medicine (geromedicine).
- Recognize emerging therapies aimed at hallmarks of aging.
- Identify ethical concerns in longevity practice.
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
Course summary
- 22.25 AAFP Prescribed
- 22.25 AAPA Category 1
- 22.25 ACHE
- 22.25 ACPE
- 22.25 AMA PRA Category 1 Credit™
- 22.25 ANCC
- 22.25 AOA Category 2-A
- 22.25 Attendance
- 22.25 IPCE
Mayo Clinic Healthy Longevity Medicine: Translating Geroscience into Clinical Practice | |
April 8, 2027 to April 10, 2027 | |
Phoenix, AZ | |
Day 1: Thursday, April 8, 2027 | |
6:50 AM | Registration, Breakfast and Exhibits |
7:50 AM | Announcements |
8:00 AM |
Keynote From Geroscience to Geromedicine: Reframing Clinical Care for Healthy Longevity Evelyne Yehudit Bischof, M.D., Ph.D.
|
8:45 AM | Biological Age Clocks: Principles, Validation, Applications, and Current Limitations Tamir Chandra, Ph.D., M.S. |
9:30 AM | The Hallmarks of Aging: Biological Mechanisms, Interconnections, and Clinical Relevance for Geromedicine Eduardo N. Chini, M.D., Ph.D. |
10:15 AM | Break |
10:30 AM | Blood biomarkers and Prevention Strategies for Alzheimer’s Disease Vijay K. Ramanan, M.D., Ph.D. |
11:00 AM | Genetics and Brain Imaging for Alzheimer Risk Assessment and Diagnosis Mary Ellen Koran, M.D., Ph.D. |
11:30 AM | Cognitive Evaluation in Clinical Settings for Brain Health and Early Detection of Cognitive Decline Dixie Woolston, Ph.D. |
12:00 PM |
Panel Roundtable Q&A Session Vijay K. Ramanan, M.D., Ph.D.; Mary Ellen Koran, M.D., Ph.D.; and Dixie Woolston, Ph.D.
|
12:30 PM | Lunch |
1:30 PM |
Whole-Body MRI for Screening in Healthy Adults: Promise, Controversies, Incidental Findings, and Evidence-based Management David Karow, M.D. |
2:15 PM | Practical Applications of Genetics/Epigenetics for Healthy Longevity Robb Rowley, M.D. |
3:00 PM | Healthy Skin Aging: A Longevity Focused Approach Saranya Wyles, M.D., Ph.D. |
3:45 PM | Break |
4:00 PM |
Optimizing Cardiovascular Healthspan: Risk Assessment and Preventive Strategies Satyajit Reddy, M.D.
|
4:45 PM |
Sleep Strategies for Healthy Aging Mithri Junna, M.D.
|
5:30 PM | Adjourn |
Day 2: Friday, April 9, 2027
| |
6:50 AM | Registration, Breakfast and Exhibits |
7:50 AM | Announcements |
8:00 AM | Exercise as Medicine and its Role in Healthy Longevity Chris Ha, D.O. |
8:30 AM | Strength, Power and Healthspan – Assessment in Clinical Settings and Exercise Prescriptions Robert Scales, Ph.D., M.S. |
9:00 AM | Cardiorespiratory Fitness and Healthy Longevity: VO₂ Peak as a Vital Sign, Prognostic Marker, and Therapeutic Target Courtney Wheatley-Guy, Ph.D. |
9:30 AM | Panel Roundtable Q&A Session Chris Ha, D.O.; Robert Scales, Ph.D., M.S.; and Courtney Wheatley-Guy, Ph.D. |
10:00 AM | Break |
10:15 AM | Optimizing Menopause Care to Support Healthy Longevity Sara Shihab, M.D. |
11:00 AM | Andropause: The Role of Testosterone in Male Healthspan Tobias Kohler, M.D., M.P.H. |
11:45 AM | Lunch |
12:45 PM |
Nutrition for Healthy Aging: From Nutrients to Nutrition Patterns Sara Bonnes, M.D., M.S.
|
1:30 PM |
Nutritional Supplements and Healthy Longevity Doina Kulick, M.D.
|
2:15 PM | Break |
2:30 PM |
New Ethics Frontiers in Geroscience and Longevity Medicine Jon Tilburt, M.D.
|
3:15 PM |
Peptides - Promise and Pitfalls Ryan Hurt, M.D.
|
4:00 PM |
Polypharmacy and Pharmacogenomics Applications to Healthy Longevity Michael Schuh, Pharm.D., R.Ph.
|
4:45 PM |
Exosome and Stem Cell Therapy - Current Applications and Future Possibilities Atta Behfar, M.D., Ph.D.
|
5:30 PM | Adjourn |
Day 3: Saturday, April 10, 2027
| |
7:00 AM | Registration, Breakfast & Exhibits |
8:00 AM | Announcements |
8:10 AM |
Repurposed FDA-Approved Drugs as Potential Geroprotectors: Mechanisms, Preclinical Evidence, Human Data, and Translational Challenges Nir Barzilai, M.D.
|
8:55 AM |
Senolytics and Senomorphics as Gerotherapeutic Strategies: Biology, Preclinical Evidence, Human Data, and Translational Challenges James Kirkland, M.D., Ph.D.
|
9:40 AM |
Cell Reprograming and Gene Editing in Longevity Medicine: Principles, Preclinical Evidence, Human Translation, and Clinical-Ethical Considerations Jay Schneider, M.D., Ph.D.
|
10:25 AM | Break |
10:45 AM |
Intrinsic Capacity as an Endpoint Biomarker for Healthy Longevity Interventions: Opportunities and Challenges Nathan K. LeBrasseur, Ph.D., M.S.
|
11:30 AM |
Clinical Research Challenges and Opportunities in Geromedicine: Trial Design, Regulatory Barriers, and Emerging Research Models Sara Espinoza, M.D.
|
12:15 PM | Lunch |
1:15 PM |
Plasma-Based Therapies in Geromedicine: From Experimental Biology to Human Evidence Pamila Brar, M.D.
|
2:00 PM | The Longevity Biotech Landscape: Separating Translational Science from Commercial HypeKarl Pfleger, Ph.D.
|
2:45 PM |
Round Table Discussion: Current State of Longevity Medicine in Clinical Practice Moderator: Atul Jain, M.D., M.S. Doina Kulick, M.D.; Sara Bonnes, M.D., M.S.; Pamila Brar, M.D.; Nir Barzilai, M.D.; James Kirkland, M.D., Ph.D.; Sara Espinoza, M.D.; Karl Pfleger, Ph.D.
|
3:45 PM | Adjourn |
A limited number of rooms are available to course attendees through courtesy room blocks at the Residence Inn and Marriott McDowell Mountain. All travel and lodging expenses are the sole responsibility of the individual registrant.
- Residence Inn: $189 per night
- Residence Inn Parking: $14 plus tax per day
- Marriott McDowell Mountain: $269 per night
- Marriott McDowell Mountain Parking: Self-parking: $25 overnight plus tax
Valet parking: $35 overnight plus tax
- Marriott McDowell Mountain Parking: Self-parking: $25 overnight plus tax
The cut-off date at the Residence Inn & Marriott McDowell Mountain is 3/8/27.
Rooms are available on a first-come, first-served basis.
Course Directors
Atul Jain, M.D., M.S.
Donia Kulick, M.D.
Sara Bonnes, M.D.
Mayo Faculty
Eduardo N. Chini, M.D., Ph.D.
Tamir Chandra, Ph.D., M.S.
Vijay K. Ramanan, M.D., Ph.D.
Mary Ellen Koran, M.D., Ph.D.
Dixie J. Woolston, Ph.D., ABPP
David Karow, M.D.
Robb Rowley, M.D.
Saranya P. Wyles, M.D., Ph.D.
Satyajit T. Reddy, M.D.
Mithri Junna, M.D.
Chris Ha, D.O.
Robert Scales, M.D., M.S.
Courtney M. Wheatley-Guy, Ph.D.
Sara Shihab, M.D.
Tobias S. Kohler, M.D., M.P.H.
Sara L. Bonnes, M.D., M.S.
Donia Kulick, M.D.
Jon C. Tilburt, M.D.
Ryan T. Hurt, M.D., Ph.D
Atta Behfar, M.D., Ph.D.
James L. Kirkland, M.D., Ph.D.
Jay W. Schneider, M.D., Ph.D.
Natahan K. LeBrasseur, Ph.D., M.D.
Jain Atul, M.D., M.S.
Guest Faculty
Nir Barzilai, M.D.
James Kirkland, M.D., Ph.D.
Evelyne Yehudit Bischof
Michael Schuh
Sara Espinoza, M.D.
Karl Pfleger
Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
Credit Statements:
AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 22.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
AAFP
Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending.
AAPA
Mayo Clinic College of Medicine and Science has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 22.25 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
ACHE
By attending the Mayo Clinic Healthy Longevity Medicine: Translating Geroscience into Clinical Practice offered by Mayo Clinic College of Medicine and Science participants may earn up to 22.25 ACHE Qualifying Education Hours toward initial certification or recertification of the Fellow of the American College of Healthcare Executives (FACHE) designation.
ACPE
Mayo Clinic College of Medicine and Science designates this educational activity for a maximum of 22.25 ACPE Knowledge-based contact hours. Participants should claim only the credit commensurate with the extent of their participation in the activity.
UAN Number: JA0000238-0000-27-013-L01-P
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 22.25 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
AOA
The American Osteopathic Association designates this program for a maximum of 22.25 AOA Category 2-A credits.
ICPE
This activity was planned by and for the healthcare team, and learners will receive 22.25 Interprofessional Continuing Education (IPCE) credit for learning and change.
Other Healthcare Professionals:
A record of attendance will be provided to all registrants for requesting credits in accordance with state nursing boards, specialty societies or other professional associations.
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Available Credit
- 22.25 AAFP Prescribed
- 22.25 AAPA Category 1
- 22.25 ACHE
- 22.25 ACPE
- 22.25 AMA PRA Category 1 Credit™
- 22.25 ANCC
- 22.25 AOA Category 2-A
- 22.25 Attendance
- 22.25 IPCE
This course offers the unique opportunity for a variety of sponsorship opportunities, including the ability to interact with healthcare providers and highlight products and services through an exhibit. The letter of request and sponsorship descriptions can be found here. W-9 attached here. Space is limited and reserved upon receipt of a completed agreement.
If you are interested in sponsoring or exhibiting at the Mayo Clinic Healthy Longevity Medicine: Translating Geroscience into Clinical Practice, complete the appropriate Letter of Agreement via the link(s) below, prior to April 8, 2027. If you do not have a profile/account you will first need to create one before completing the online form:
- If you are interested in participating, please complete the Exhibitor Letter of Agreement.
Contact: Latasha Bunkley with questions.
Before registering, please update your profile
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Every effort will be made to accommodate dietary requirements; however, some requests may not be feasible based on venue kitchen capabilities. Attendees will be contacted in advance if a dietary restriction cannot be fulfilled.
The Mayo Clinic School of Continuous Professional Development strives for fully accessible learning experiences. If you anticipate any barriers while attending this course, please reach out to the course coordinator who will be in touch with all registrants. If you need disability-related accommodations, please contact the Office of Wellness and Academic Support – Disability Access Services at MCCMS.DS@mayo.edu.
Cancellation and Refund Policy
View Cancellation and Refund Policy
All requests must be submitted in writing using the Contact Us Form.
Any use of this site constitutes your agreement to the Terms and Conditions of Registration.

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