Session date: 
02/25/2026 - 12:00pm to 1:00pm

PRESENTATION TITLE

Translational Approach to Cutaneous Squamous Cell Carcinoma 

PRESENTER(S)
John A. Carucci, M.D.

LEARNING OBJECTIVES
Upon completion of this activity, participants should be able to:

  • Identify clinical and pathologic features associated with high-risk cutaneous squamous cell carcinoma, including predictors of metastasis and disease-specific mortality.​

  • Apply core principles of translational medicine to dermatologic oncology by linking clinical observations to biomarker and therapeutic target discovery.​

  • Describe key immune mechanisms driving cSCC progression, including IL-22/JAK-STAT signaling and PD-1/PD-L1 checkpoint pathways.​

  • Assess emerging translational strategies in advanced cSCC, including immunotherapy, single-cell and spatial transcriptomic profiling, and AI-enabled histopathologic risk prediction.

ATTENDANCE / CREDIT
Text the session code (provided only at the session) to 507-200-3010 within 48 hours of the live presentation to record attendance. All learners are encouraged to text attendance regardless of credit needs. This number is only used for receiving text messages related to tracking attendance. Additional tasks to obtain credit may be required based on the specific activity requirements and will be announced accordingly. Swiping your badge will not provide credit; that process is only applicable to meet GME requirements for Residents & Fellows.

TRANSCRIPT
Any credit or attendance awarded from this session will appear on your Transcript.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.

Presenter: 
John A. Carucci, MD
Where did the idea for the course originate?: 
Arizona
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Where did the idea for the course originate?: 
Arizona