Pharmacy Grand Rounds
Are you a 10/10? Tenecteplase in Ischemic Stroke

• ACPE Universal Activity Number (UAN): JA0000238-0000-20-028-L01-P
• Session Type: Knowledge-based
• CE Credits: A maximum of 0.75 contact hour (0.075 CEU) for the following: 
  • AAPA Category 1 CME Credits
  • ACPE
  • AMA PRA Category 1 Credits™
  • ANCC

• Session Fee: Free for Mayo Clinic staff

SESSION LOCATIONS

Live Session: (11:00am - 11:45am CST) 

Until further notice, learners must watch Pharmacy Grand Rounds live via the web by going to the Video Exchange and selecting “Pharmacy Grand Rounds” in the “Streaming Now” section.

Participants may attend by viewing: Live Webcast
Video Recording - access two weeks after session date

COURSE DESCRIPTION

In the 2019 Update to the Guidelines for the Early Management of Patients with Acute Ischemic Stroke, the American Heart Association and American Stroke Association included tenecteplase as a thrombolytic option for reperfusion therapy. The recommendation suggests it may be reasonable use tenecteplase instead of alteplase, in patients eligible for mechanical thrombectomy and without contraindications to systemic thrombolysis. At this time, alteplase remains the standard as most accredited stroke centers have yet to widely adopt tenecteplase into clinical practice. This presentation will examine the data regarding tenecteplase in acute ischemic stroke and will discuss its place in therapy.

At the conclusion of this knowledge-based CE session, participants should be able to:

• Describe the differences between thrombolytic agents used for the treatment of ischemic stroke
• Discuss the literature examining the efficacy and safety outcomes of tenecteplase
• Identify the role of tenecteplase in ischemic stroke thrombolysis

Session Announcement

Session Sldes

FACULTY INFORMATION

Cassandra J. Schmitt, PharmD
PGY1 Pharmacy Resident
Mayo Clinic Hospital - Rochester, MN

Cassandra received a Doctor of Pharmacy degree from Virginia Commonwealth University in Richmond, Virginia.  She is a current PGY1 Pharmacy Resident at Mayo Clinic Hospital – Rochester with clinical practice interests in emergency medicine and leadership.  

DISCLOSURE STATEMENTS

As a provider accredited by Joint Accreditation Interprofessional Continuing Education, Mayo Clinic College of Medicine and Science (Mayo Clinic School of CPD) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course Director(s), Planning Committee Members, Faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of these relevant financial relationships will be published in activity materials so those participants in the activity may formulate their own judgments regarding the presentation.

Listed below are individuals with control of the content of this program:

The faculty report the following relationships:

• Cassandra J. Schmitt, PharmD
  • Declares no financial relationships pertinent to this session
  • Declares off-label use of devices and medications will be discussed during this presentation, including;
    • Tenecteplase

Course Director and Planning Committee Members declare no relevant financial relationship(s) pertinent to this session.  Members include:

• Brenda Amaris
• Mary Ellen Cordes, MS, APRN, CNC, NE-BC
• Jennifer Elmer, DNP, APRM, CCNS, FCCM
• Michael Huckabee, MPAS, PA-C, PhD
• Wayne (Nick) Nicholson, MD, PharmD, BCPS
• Garrett Schramm, PharmD, BCPS
• Lee Skrupky, PharmD, BCPS