Pharmacy Grand Rounds
Once in a Blue Moon: Methylene Blue for Catecholamine-Refractory Shock in Pediatric Patients

• ACPE Universal Activity Number (UAN): JA0000238-0000-20-028-L01-P
• Session Type: Knowledge-based
• CE Credits: A maximum of 0.75 contact hour (0.075 CEU) for the following: 
  • AAPA Category 1 CME Credits
  • ACPE
  • AMA PRA Category 1 Credits™
  • ANCC

• Session Fee: Free for Mayo Clinic staff

SESSION LOCATIONS

Live Session: (11:00am - 11:45am CST) 

Until further notice, learners must watch Pharmacy Grand Rounds live via the web by going to the Video Exchange and selecting “Pharmacy Grand Rounds” in the “Streaming Now” section.

Participants may attend by viewing: Live Webcast
Video Recording - access two weeks after session date

COURSE DESCRIPTION
Guideline-recommended treatment options for catecholamine-refractory shock have shown mixed results in the adult population and have scarce data in use in the pediatric population. Methylene blue is one of the more recent treatment options that has not quite been recognized in guidelines for various types of shocks, but has shown promise in adult studies and in pediatric studies on a smaller scale. This presentation will review recent evidence regarding the use of methylene blue in catecholamine-refractory shock in pediatric patients and its clinical utility.

At the conclusion of this knowledge-based CE session, participants should be able to:

• Describe the mechanism of action of methylene blue in the context of shock
• Review literature supporting the use of methylene blue for refractory shock in pediatric patients
• Identify clinical factors in which methylene blue can be considered for treatment of refractory shock

Session Announcement

Presentation Slides.pdf

FACULTY INFORMATION

Mai UyenAlissa Le, PharmD
PGY1 Pharmacy Resident (Pediatrics-Focused)
Mayo Eugenio Litta Children's Hospital - Rochester, MN

Mai received a Doctor of Pharmacy degree from Temple University School of Pharmacy in Philadelphia, PA.  She is a current PGY-1 Pharmacy Resident at Mayo Eugenio Litta Children’s Hospital with clinical practice interests in general pediatrics and critical care.  

DISCLOSURE STATEMENTS
As a provider accredited by Joint Accreditation Interprofessional Continuing Education, Mayo Clinic College of Medicine and Science (Mayo Clinic School of CPD) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course Director(s), Planning Committee Members, Faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of these relevant financial relationships will be published in activity materials so those participants in the activity may formulate their own judgments regarding the presentation.

Listed below are individuals with control of the content of this program:

The faculty report the following relationships:

• Mai Uyen Alissa Le, PharmD
  • Declares no financial relationships pertinent to this session
  • Declares off-label use of devices and medications will be discussed during this presentation, including;
    • Methylen blue

Course Director and Planning Committee Members declare no relevant financial relationship(s) pertinent to this session.  Members include:

• Brenda Amaris
• Mary Ellen Cordes, MS, APRN, CNC, NE-BC
• Jennifer Elmer, DNP, APRM, CCNS, FCCM
• Michael Huckabee, MPAS, PA-C, PhD
• Wayne (Nick) Nicholson, MD, PharmD, BCPS
• Garrett Schramm, PharmD, BCPS
• Lee Skrupky, PharmD, BCPS