Pharmacy Grand Rounds
To Be or Not to Be: Benefits and Challenges of 340B

• ACPE Universal Activity Number (UAN): JA0000238-0000-21-004-L01-P
• Session Type: Knowledge-based
• CE Credits: A maximum of 0.75 contact hour (0.075 CEU) for the following: 
  • AAPA Category 1 CME Credits
  • ACPE
  • AMA PRA Category 1 Credits™
  • ANCC

• Session Fee: Free for Mayo Clinic staff

SESSION LOCATIONS

Live Session: (11:00am - 11:45am CST) 

Until further notice, learners must watch Pharmacy Grand Rounds live via the web by going to the Video Exchange and selecting “Pharmacy Grand Rounds” in the “Streaming Now” section.

Participants may attend by viewing: Live Webcast
Video Recording - access two weeks after session date

COURSE DESCRIPTION
There are approximately 20,000 new cases of acute myeloid leukemia (AML) annually in the United States and over 95% of cases harbor at least one genetic mutation. With advancements in technology and next-generation sequencing, a prognostic schema has been developed that divides patients into 3 groups based on cytogenetics correlating to 5-year overall survival rate. There have been several targeted therapies recently approved, but a large proportion of patients with AML lack targetable mutations. During this presentation we will review background information of AML, review literature supporting induction regimens for patients without targetable mutations, and discuss how to select between regimens based on specific patient factors.

LEARNING OBJECTIVES
At the conclusion of this knowledge-based CE session, participants should be able to:

• Describe epidemiology, pathophysiology, and prognosis of acute myeloid leukemia (AML).
• Review literature supporting induction regimens for patients with AML without targetable mutations.
• Discuss how to select between AML induction regimens based on patient-specific factors

Session Announcement.pdf

PowerPoint.pdf

FACULTY INFORMATION

Allison P. Golbach, PharmD, BCPS
PGY2 Oncology Pharmacy Resident
Mayo Clinic Hospital - Rochester, MN

Allison received a Doctor of Pharmacy degree from Drake University and subsequently completed a PGY1 Pharmacy Residency at Mayo Clinic Hospital – Rochester. She is a current PGY2 Oncology Pharmacy Resident at Mayo Clinic Hospital-Rochester with practice interests in hematology, oncology, and pharmacogenomics.

DISCLOSURE STATEMENTS
As a provider accredited by Joint Accreditation Interprofessional Continuing Education, Mayo Clinic College of Medicine and Science (Mayo Clinic School of CPD) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course Director(s), Planning Committee Members, Faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of these relevant financial relationships will be published in activity materials so those participants in the activity may formulate their own judgments regarding the presentation.

Listed below are individuals with control of the content of this program:

The faculty report the following relationships:

• Allison P. Golbach, PharmD, BCPS
  •  
  • Declares no financial relationship(s) pertinent to this session
  • Declares off-label use of devices and medications will be discussed during this presentation, including:
    • Azacitadine
    • Cytarabine
    • Daunorubicin
    • Decitabine
    • Filgrastim
    • Fludarabine
    • Glasdegib
    • Idarubicin
    • Liposomal daunorubicin/cytarabine
    • Pegfilgrastim
    • Venetoclax

Course Director and Planning Committee Members declare no relevant financial relationship(s) pertinent to this session. 

Members include:

• Jennifer Elmer, DNP, APRM, CCNS, FCCM
• Michael Huckabee, MPAS, PA-C, PhD
• Sarah Jane Kotval
• Wayne (Nick) Nicholson, MD, PharmD, BCPS
• Garrett Schramm, PharmD, BCPS
• Lee Skrupky, PharmD, BCPS
• Brenda Stellmaker