Speaker: Jesse Burson, DO

Title: Metabolic Medications, Toxic Consequences: GLP-1 Receptor Agonists and Drugs with a Narrow Therapeutic Index

Introduction: 

Jesse Ray Burson, D.O. is a PGY-4 psychiatry resident at Mayo Clinic. He completed his undergraduate degree in biomedical sciences with minors in chemistry and psychology at northern Arizona University and completed his medical training at Rocky Vista University in Colorado. His clinical and academic interests include acute psychiatric care, consultative psychiatry, and the treatment of individuals with severe and persistent mental illness. Dr. Burson has previously published work on phenibut intoxication and withdrawal, defining treatment-resistant substance use disorder, and recently had a case report accepted for publication regarding lithium toxicity and tirzepatide initiation. He is currently conducting research examining the relationship between GLP-1 receptor agonist initiation or dose adjustments and lithium serum levels. Today, Dr. Burson will present a brief overview of GLP-1 receptor agonists and their effects on psychiatric medications with narrow therapeutic indices, along with preliminary data from his ongoing research. 

Learning Objectives: 
Upon completion of this activity, participants should be able to:

• • Recognize current prescribing patterns of GLP-1 receptor agonists and their relevance to psychiatric practice​ 

  • Identify potential interactions between GLP-1 receptor agonists and psychiatric medications with narrow therapeutic indices, focusing on clozapine, lamotrigine, and lithium.​ 

  • Apply available case-based evidence and emerging research to inform monitoring strategies when initiating, discontinuing, or adjusting GLP-1receptor agonists in patients receiving narrow therapeutic index psychiatric medications. 

ATTENDANCE / CREDIT
Text the session code (provided only at the session) to 507-200-3010 within 48 hours of the live presentation to record attendance. All learners are encouraged to text attendance regardless of credit needs. This number is only used for receiving text messages related to tracking attendance. Additional tasks to obtain credit may be required based on the specific activity requirements and will be announced accordingly. Swiping your badge will not provide credit; that process is only applicable to meet GME requirements for Residents & Fellows.

TRANSCRIPT
Any credit or attendance awarded from this session will appear on your Transcript.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.