A Systematic Approach to Medically Unexplained Symptoms 2027
This course offers Live (in-person) and Livestream (virtual) attendance options

Course Directors: Michael R. Mueller, MD and Elizabeth C. Wight, MD
August 11-14, 2027 - Hyatt at Olive 8 - Seattle, Washington
All scheduled times are in the Pacific Time Zone
Join us in Seattle, WA, August 11-14, 2027, at the elegant Hyatt at Olive 8 for an inspiring CME experience where cutting-edge education, meaningful connections, and the vibrant energy of the Pacific Northwest come together to elevate your practice and recharge your professional passion.
This course offers evidence-based strategies for managing medically unexplained conditions. Review of the pathophysiological process of nociplastic pain will be followed by symptom-specific didactic sessions, case vignettes, clinical pearls, Q&A sessions, daily roundtable discussions and group problem-solving exercises.
*To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery and post-course recordings will not be available. Livestream will be presented as voiceover PowerPoint only, with no live camera feed on the presenter.
Notify Me When A Systematic Approach to Medically Unexplained Symptoms 2027 Registration Opens
Signing up to be notified will ensure that you receive an email when registration opens. No additional information is available until then.
Target Audience
This course is intended for general internists, internal medicine subspecialists, family medicine physicians, physician assistants, nurse practitioners, and other primary healthcare professionals who practice in or have a special interest in treating medically complex patients.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Differentiate between nociceptive, neuropathic, and nociplastic pain mechanisms
- Evaluate postural orthostatic tachycardia syndrome
- Critique common patient-reported etiologies using current evidence bases to provide empathetic and scientifically accurate counseling
- Apply practical nonpharmacologic strategies for management of chronic pain, fatigue, orthostatic intolerance, and brain fog
- Identify treatment strategies for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
All travel and lodging expenses are the sole responsibility of the individual registrant.
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Thank you for your interest in A Systematic Approach to Medically Unexplained Symptoms 2027. This course is currently in the early planning stages. If you’d like to be notified when opportunities become available, please add your name to our Notify Me list. Signing up to be notified will ensure that you receive an email when exhibitor information is available. No additional information is available until then.
Notify Me When A Systematic Approach to Medically Unexplained Symptoms 2027 Registration Opens
Signing up to be notified will ensure that you receive an email when registration opens. No additional information is available until then.
Please update your profile
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Every effort will be made to accommodate dietary requirements; however, some requests may not be feasible based on venue kitchen capabilities. Attendees will be contacted in advance if a dietary restriction cannot be fulfilled.
The Mayo Clinic School of Continuous Professional Development strives for fully accessible learning experiences. If you anticipate any barriers while attending this course, please reach out to the course coordinator who will be in touch with all registrants. If you need disability-related accommodations, please contact the Office of Wellness and Academic Support – Disability Access Services at MCCMS.DS@mayo.edu.
Cancellation and Refund Policy
View Cancellation and Refund Policy
All requests must be submitted in writing using the Contact Us Form.
Any use of this site constitutes your agreement to the Terms and Conditions of Registration.

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