April 2-4, 2027 - Mayo Clinic - Phoenix, Arizona

This course is offered Live (in-person) only

Designed for experienced practitioners in operational aerospace medicine, the program emphasizes practical solutions to complex problems encountered during astronaut training, in-flight health maintenance, and post-mission rehabilitation. Participants will engage in confidential, small-group discussions on topics such as decompression sickness, hypoxia, radiation exposure, life-support systems, and emerging diagnostic and treatment methods for spaceflight environments.

April 8 -10, 2027 - Laguna Cliffs Marriott Resort & Spa - Dana Point, California

This course offers Live (in-person) and Livestream (virtual) attendance options

This comprehensive course addresses pain conditions across multiple medical disciplines, aiming to enhance pain management and improve patient outcomes. Through a structured series of lectures, participants explore the full spectrum of chronic pain treatment, including pharmacologic therapies, non-pharmacologic approaches, and interventional procedures. This course includes presentations focusing on strategies for perioperative and inpatient pain management, offering practical insights for clinical application. The curriculum also delves into the evaluation and treatment of common comorbidities associated with chronic pain—such as central sensitization, depression, and anxiety—with particular emphasis on the role of cognitive behavioral therapy. Additionally, the course provides an in-depth review of prevalent pain syndromes, including spine pain, neuropathic pain, headache, fibromyalgia, chronic fatigue syndrome, and arthritic conditions.

April 8 - 10, 2027 - Integrated Education and Research Building - Phoenix, Arizona

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic Healthy Longevity Medicine is a comprehensive CME course designed to provide clinicians with clinically relevant knowledge in the emerging discipline of longevity medicine. The course delivers a structured curriculum focused on applying aging biology to patient care, with an emphasis on prevention, early risk detection, and healthspan extension. Participants will examine key biological mechanisms of aging—the hallmarks of aging—and explore how these processes contribute to functional decline, chronic disease risk, and potential targets for clinical intervention. The course covers a wide range of topics, including biomarkers of aging (biological age clocks), multidimensional assessment in geromedicine, lifestyle interventions, and emerging pharmacologic and regenerative therapies. Led by faculty from Mayo Clinic, alongside invited experts from national and international academic institutions, the course features a blend of didactic lectures and interactive case-based discussions. The course places emphasis on the critical appraisal of translational and clinical trials and the ethical considerations unique to the practice of geromedicine. Upon completion, participants will be equipped to thoughtfully integrate principles of geromedicine into their clinical care and contribute to the responsible advancement of longevity medicine.

April 23-24, 2027 - The Westin Carlsbad Resort & Spa - Carlsbad, CA

This course offers Live (in-person) and Livestream (virtual) attendance options

Join leading academic, clinical, and industry experts to explore innovations that are transforming early cancer detection. This activity highlights advances in multi-cancer detection (MCD) as a population screening tool, cell-free DNA (cfDNA), multi-modal detection platforms and precision cancer treatment while addressing clinical implementation, collaboration, and strategies to accelerate translation into practice.

General Session: April 29 - May 1, 2027 - JW Marriott Tucson Starr Pass Resort & Spa - Tucson, Arizona

Special Feature: Pediatric Palliative Cases (Pre-Course Session Day) April 28, 2027. This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's Updates in Palliative Care is a multidisciplinary CME course designed to build and enhance your palliative care knowledge. Experts from Mayo Clinic provide clinically relevant pearls for palliative care providers and clinicians from primary care, hematology/oncology, hospital medicine, critical care, pediatrics, and related specialties. If you care for patients with serious illness and are looking to broaden your skills beyond the basics, this is the course for you.

April 30 - May 1, 2027 - Mayo Clinic - Rochester, Minnesota

This course offers Live (in-person) and Livestream (virtual) attendance options

This Mayo Clinic course, specifically designed for infectious diseases practitioners, focuses exclusively on the complexities of managing orthopedic infections. It features dynamic, case-based modules led by experts in the field, addressing both diagnostic and therapeutic challenges. Key topics include controversies and updates in the use of DAIR (debridement, antibiotics, and implant retention) for prosthetic joint infections, the role of dalbavancin in treatment regimens, and strategies for managing fracture-related infections. Each session is followed by engaging, case-based group discussions, facilitated by a panel of seasoned professionals.