Hepatology and Liver Transplantation: Today and Tomorrow 2027
This course offers Live (in-person) and Livestream (virtual) attendance options

Course Directors: Tushar C. Patel, M.B., Ch.B., Andrew P. Keaveny, M.D., and Kristen L. Ryland, APRN
June 11-12, 2027 - Orlando, Florida
Hepatology and Liver Transplantation: Today and Tomorrow 2027 brings together leading experts to examine the latest advances transforming the care of patients with liver disease. Through dynamic lectures, case-based discussions, debates, and interactive breakout sessions, participants explore cutting-edge developments in liver transplantation, liver cancer, cirrhosis, acute and chronic liver failure, metabolic and cholestatic liver diseases, endohepatology, artificial intelligence, and digital health. Emphasizing multidisciplinary, patient-centered care, the program delivers practical, evidence-based strategies that clinicians can immediately apply to improve outcomes and navigate the evolving landscape of liver disease management.
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Target Audience
This course is intended for gastroenterologists, hepatologists, primary care providers, nurse practitioners, and physician assistants specializing in gastroenterology and endocrinology. It may also be beneficial for other primary care professionals.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Identify current evidence-based approaches to the management of acute and chronic liver failure.
- Identify emerging trends and evidence-based approaches in the diagnosis and management of MASLD, Met-ALD, liver cancer, and liver transplantation.
- Explain innovations occurring in the management of liver diseases, including viral hepatitis and cholestatic liver diseases.
- Discuss current new developments and team-based management of hepatology and in liver transplantation.
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
Course summary
Hepatology and Liver Transplantation: Today and Tomorrow 2027 |
Waldorf Astoria Orlando Orlando, Florida |
June 11-12, 2027 |
All Presentations Eastern Time |
Friday, June 11, 2027 | |
7:00 AM | Registration, Breakfast and Exhibits |
8:00 AM | Welcome Introductions Andrew P. Keaveny, M.D., Mayo Clinic Florida |
| Preparing for the Future Chair: Tushar Patel, M.B., Ch.B., Mayo Clinic Florida |
8:05 AM
| The future of Hepatology Tushar Patel, M.B., Ch.B., Mayo Clinic Florida |
8:15 AM | Treatment of chronic hepatitis B & D: Aiming for cure Hugo E. Vargas, M.D., Mayo Clinic Arizona |
8:45 AM | Endohepatology in practice Vivek Kumbhari, M.B., Ch.B., Ph.D., Mayo Clinic Florida |
9:15 AM | AI and digital tools to enhance your practice Sushil Kumar Garg, M.B.B.S., Mayo Clinic Florida |
9:45 AM | Q and A Session Moderator: Tushar Patel, M.B., Ch.B., Mayo Clinic Florida Panelists: Hugo E. Vargas, M.D., Mayo Clinic Arizona Vivek Kumbhari, M.B., Ch.B., Ph.D., Mayo Clinic Florida Sushil Kumar Garg, M.B.B.S., Mayo Clinic Florida |
10:00 AM | Coffee Break and Exhibits |
| Immune and Cholestatic Liver Diseases Chair: Kymberly D. Watt M.D., Mayo Clinic Rochester |
10:20 AM | Evaluation of a patient with cholestasis Denise M. Harnois, D.O., Mayo Clinic Florida |
10:40 AM | Update on treatment of PBC and PSC John E. Eaton, M.D., Mayo Clinic Rochester |
11:00 AM | Diseases of iron and copper affecting the liver Michele Barnhill, M.D., Mayo Clinic Arizona |
11.20 AM | Genetic diseases in the liver: A1AT, PFIC in adults, APKLD, Telomere biology disorders Omar Y. Mousa, M.B.B.S., M.D., Mayo Clinic Florida |
11:35 AM | Q and A Session and Case discussions Moderator: Doug A. Simonetto, M.D., Mayo Clinic Rochester Panelists: Denise M. Harnois, D.O., Mayo Clinic Florida John E. Eaton, M.D., Mayo Clinic Rochester Michele Barnhill, M.D., Mayo Clinic Arizona Omar Y. Mousa, M.B.B.S., M.D., Mayo Clinic Florida |
11:45 PM | Lunch |
*12:45-1:15 PM | Breakout session 1: Financial wellness |
| Your biggest asset isn’t what you think Tushar Patel, MBChB, Mayo Clinic Florida |
| Obesity and the Liver Chair: Manal F. Abdelmalek, M.D., Mayo Clinic Rochester |
1:20 PM | Nutrition in the era of GLP-1s: practical counselling Lindsey A. Russell, M.D., Mayo Clinic Florida |
1:40 PM | Medical options for the obese patient Kirsten E. Frederiksen, M.D., M.S., Mayo Clinic Florida |
2:10 PM | Endobariatric therapies for weight loss Dilhana S. Badurdeen, M.B.B.S., M.D., Mayo Clinic Florida |
2:30 PM | Bariatric surgery: Approaches, and common complications after surgery Omar M. Ghanem, M.D., Mayo Clinic Rochester |
2:50 PM | Q and A Session Moderator: Manal F. Abdelmalek, M.D., Mayo Clinic Rochester Panelists: Lindsey A. Russell, M.D., Mayo Clinic Florida Kirsten E. Frederiksen, M.D., M.S., Mayo Clinic Florida Dilhana S. Badurdeen, M.B.B.S., M.D., Mayo Clinic Florida Omar M. Ghanem, M.D., Mayo Clinic Rochester |
3:10 PM | Coffee Break and Exhibits |
| Managing the Damaged Liver Chair: Omar Y. Mousa, M.B.B.S., M.D., Mayo Clinic Florida |
3:30 PM | State-of-the art: Managing drug-induced liver injury Robert J. Fontana, M.D., University of Michigan Health |
4:10 PM | Pain management and liver disease Christy L. Hunt, D.O., Mayo Clinic Florida |
4.30 PM | Update on Liver transplantation Kymberly D. Watt, M.D., Mayo Clinic Rochester |
4.50 PM | Q and A Session Moderator: Omar Y. Mousa, M.B.B.S., M.D., Mayo Clinic Florida Panelists: Robert J. Fontana, M.D., University of Michigan Health Christy L. Hunt, D.O., Mayo Clinic Florida Kymberly D. Watt, M.D., Mayo Clinic Rochester |
5:00 PM | Closing remarks Tushar Patel, M.B., Ch.B., Mayo Clinic Florida |
5:05 PM | Networking Reception and Poster Session |
6:15 PM | ADJOURN – End of Day 1 |
Saturday, June 12, 2027 | |
7:00 AM | Registration, Breakfast and Exhibits |
7:55 AM | Welcome and Introductions Andrew P. Keaveny, M.D., Mayo Clinic Florida |
| Hospital Hepatology Chair: Andrew P. Keaveny, M.D., Mayo Clinic Florida |
8:00 AM
| Acute on chronic liver failure Jacqueline G. O'Leary, M.D., Dallas VA Med Center |
8:30 AM
| GI bleeding in cirrhosis – the GI perspective Philip N. Okafor, M.D., Mayo Clinic Florida |
8:50 AM | GI bleeding in cirrhosis – the Hepatology perspective Blanca C. Lizaola-Mayo, M.D., Mayo Clinic Arizona |
9:10 AM | GI bleeding – the IR perspective Andrew R. Lewis, M.D., Mayo Clinic Florida |
9:30 AM | Pre and periop management of patients with cirrhosis – the anesthesiology perspective Beth L. Ladlie, M.D., M.P.H., Mayo Clinic Florida |
9.45 AM | Q and A Session Moderator: Andrew P. Keaveny, M.D., Mayo Clinic Florida Panelists: Jacqueline G. O'Leary, M.D., Dallas VA Med Center Philip N. Okafor, M.D., Mayo Clinic Florida Blanca C. Lizaola-Mayo, M.D., Mayo Clinic Arizona Andrew R. Lewis, M.D., Mayo Clinic Florida Beth L. Ladlie, M.D., M.P.H., Mayo Clinic Florida |
10.00 AM | Coffee Break and Exhibits |
| The Patient with Cirrhosis Chair: Blanca C. Lizaola-Mayo, M.D., Mayo Clinic Arizona |
10:15 AM | Caring for patients with cirrhosis: Home monitoring, diet, education, palliative care Doug A. Simonetto, M.D., Mayo Clinic Rochester |
10:35 AM | Q and A Session |
10:40 AM | Managing kidney disease and renal failure Hani M. Wadei, M.D., Mayo Clinic Florida |
11:00 AM | Q and A Session |
11:05 AM | Diagnosis and management of hepatic encephalopathy Nicole M. Loo, M.D., Mayo Clinic Florida |
11:25 AM | Q and A Session |
11:30 AM | Debate – All patients with cirrhosis should have a screening EGD Moderator: Blanca C. Lizaola-Mayo, M.D., Mayo Clinic Arizona Yes: Michael D. Leise, M.D., Mayo Clinic Rochester (8 min) No: Andrew P. Keaveny, M.D., Mayo Clinic Florida (8 min) Rebuttal (3 min each) |
12:00 PM | Lunch and Non-CME Product theatre (end by 12:35 pm) |
*12:40-1:10 PM | Breakout session 2: Professional development |
| APP professional development Kaitlyn R. Musto, P.A.-C., Mayo Clinic Florida |
| Cancer in the Liver Chair: Denise M. Harnois, D.O., Mayo Clinic Florida |
1:15 PM | Medical management of HCC Conor D. O'Donnell, M.B., B.Ch., B.A.O., Mayo Clinic Florida |
1:35 PM | Surgery and liver transplantation for HCC Shennen A. Mao, M.D., Mayo Clinic Florida |
1:55 PM | Biliary tract cancers Sumera I. Ilyas, M.B.B.S., Mayo Clinic Rochester |
2:15 PM | Liver transplant for non-HCC cancer indications Kris P. Croome, M.D., Mayo Clinic Florida |
2:35 PM | Q and A Session Moderator: Denise M. Harnois, D.O., Mayo Clinic Florida Panelists: Conor D. O'Donnell, M.B., B.Ch., B.A.O., Mayo Clinic Florida Shennen A. Mao, M.D., Mayo Clinic Florida Sumera I. Ilyas, M.B.B.S., Mayo Clinic Rochester Kris P. Croome, M.D., Mayo Clinic Florida |
3:00 PM | Coffee Break and Exhibits |
| Hot Topics in Liver Diseases Chair: Hugo E. Vargas, M.D., Mayo Clinic Arizona |
3:30 PM | Acute liver failure: diagnosis, prognosis, management Jody C. Olson, M.D., Mayo Clinic Rochester |
3:50 PM | MASLD State of the art in 2027 Manal F. Abdelmalek, M.D., Mayo Clinic Rochester |
4:20 PM | Optimal management for Met-ALD and ALD Karn Wijarnpreecha, M.D., M.P.H., Mayo Clinic Florida |
4:55 PM | Q and A Session Moderator: Hugo E. Vargas, M.D., Mayo Clinic Arizona Panelists: Jody C. Olson, M.D., Mayo Clinic Rochester Manal F. Abdelmalek, M.D., Mayo Clinic Rochester Karn Wijarnpreecha, M.D., M.P.H., Mayo Clinic Florida |
5:10 PM | Closing Remarks Kristen L. Ryland, APRN, Mayo Clinic Florida |
5:15 PM | ADJOURN – End of Day 2 |
Experience the elegance and exceptional hospitality of Waldorf Astoria Orlando, a premier luxury destination nestled amid beautiful natural surroundings. Guests can enjoy spacious accommodations, award-winning dining, world-class amenities, and the personalized service for which Waldorf Astoria is renowned.
A block of rooms has been reserved for attendees at a group rate starting at $389 per night, plus applicable taxes and resort fee of $30 per night.
Make your reservations before the room block sells out or before the expiration date of May 20, 2027, whichever comes first. The discounted room reservation link will be included in the confirmation email after enrollment is complete.
All travel and lodging expenses are the sole responsibility of the individual registrant.
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Thank you for your interest in Hepatology and Liver Transplantation: Today and Tomorrow 2027. This course is currently in the early planning stages. If you’d like to be notified when opportunities become available, please add your name to our Notify Me list. Signing up to be notified will ensure that you receive an email when exhibitor information is available. No additional information is available until then.
Notify me when Hepatology and Liver Transplantation: Today and Tomorrow 2027 registration opens
Signing up to be notified will ensure that you receive an email when registration opens. No additional information is available until then.
Before registering, please update your profile
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Every effort will be made to accommodate dietary requirements; however, some requests may not be feasible based on venue kitchen capabilities. Attendees will be contacted in advance if a dietary restriction cannot be fulfilled.
The Mayo Clinic School of Continuous Professional Development strives for fully accessible learning experiences. If you anticipate any barriers while attending this course, please reach out to the course coordinator who will be in touch with all registrants. If you need disability-related accommodations, please contact the Office of Wellness and Academic Support – Disability Access Services at MCCMS.DS@mayo.edu.
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