April 8 - 10, 2027 - Integrated Education and Research Building - Phoenix, Arizona This course offers Live (in-person) and Livestream (virtual) attendance options Mayo Clinic Healthy Longevity Medicine is a comprehensive CME course designed to provide clinicians with clinically relevant knowledge in the emerging discipline of longevity medicine. The course delivers a structured curriculum focused on applying aging biology to patient care, with an emphasis on prevention, early risk detection, and healthspan extension. Participants will examine key biological mechanisms of aging—the hallmarks of aging—and explore how these processes contribute to functional decline, chronic disease risk, and potential targets for clinical intervention. The course covers a wide range of topics, including biomarkers of aging (biological age clocks), multidimensional assessment in geromedicine, lifestyle interventions, and emerging pharmacologic and regenerative therapies. Led by faculty from Mayo Clinic, alongside invited experts from national and international academic institutions, the course features a blend of didactic lectures and interactive case-based discussions. The course places emphasis on the critical appraisal of translational and clinical trials and the ethical considerations unique to the practice of geromedicine. Upon completion, participants will be equipped to thoughtfully integrate principles of geromedicine into their clinical care and contribute to the responsible advancement of longevity medicine.