Multiple Sclerosis and Autoimmune Neurology Update 2027
This course offers Live (in-person) and Livestream (virtual) attendance options

Course Directors: Mark Keegan, M.D., Eoin Flanagan, M.B., B.Ch., Samantha Banks, M.D., and Sarosh Irani, B.M., B.Ch., D.Phil.
February 1 - 4, 2027 - The Westin Hapuna Beach Resort - Waimea, Hawaii
A state-of-the-art update on multiple sclerosis and autoimmune neurology, offering evidence-based, practical, multidisciplinary care strategies. Open to all healthcare professionals interested in this field. Features the latest clinical and laboratory research through lectures, case vignettes, and interactive discussions with expert presenters.
To see the course fee, please log in or create an account
| Registration Fee(s) | |
|---|---|
| M.D., D.O., Ph.D. | $1195 |
| Allied Health, NP, PA, Retirees | $975 |
Target Audience
Includes: allied health professionals; nurses; nurse practitioners; physicians; physician assistants; resident/fellows; healthcare executives, pharmacists, physical and occupational therapists, and social workers.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Differentiate Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorder (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody Disease (MOGAD)
- Identify neurologic infections associated with different immunosuppressant medications in MS and autoimmune neurology patients
- Identify the correct neural antibody test to order when evaluating autoimmune neurological disorders
- Describe the therapeutic approach to autoimmune encephalitis
- Identify the role of novel Btk inhibitors in the management of multiple sclerosis
- Be aware of the updated diagnostic criteria for NMOSD and its application in clinical practice
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
Monday, February 1, 2027 | ||
Multiple Sclerosis Assessment – Moderated by Mark Keegan, M.D. | ||
6:30 – 7:20 | Breakfast and Registration | |
Meet the Course Director Workshop (optional): | ||
7:20 – 7:30 | Announcements | |
7:30 – 8:10 | 2024 Revised Diagnostic Criteria for Multiple Sclerosis: How Do They Change Practice? | |
7:55 – 8:05 | Case Discussions in MS Diagnosis | |
8:05 – 8:10 | Questions | |
8:10 – 8:50 | RIS, Prodromal and Asymptomatic MS | |
8:35 – 8:45 | Cases in RIS | |
8:45 – 8:50 | Questions | |
8:50 – 9:05 | Break | |
9:05 – 9:45 | Assessment and Differential Diagnosis of Tumefactive Forms of MS | |
9:30 – 9:40 | Cases in Tumefactive MS and Mimics | |
9:40 – 9:45 | Questions | |
9:45 – 10:25 | Updates in Assessment of Progressive Multiple Sclerosis | |
10:10 – 10:20 | Case Discussions in Progressive MS Diagnosis | |
10:20 – 10:25 | Questions | |
10:25 – 10:40 | Break | |
10:40 – 11:20 | Optic Neuritis in MS | |
11:05 – 11:10 | Cases in MS Optic Neuritis | |
11:10 – 11:15 | Questions | |
11:20 – 12:00 | Pediatric MS: What Is It and How Do We Treat It? | |
11:45 – 11:55 | Cases in Pediatric MS | |
11:55 – 12:00 | Questions | |
Tuesday, February 2, 2027 | ||
Autoimmune CNS Demyelinating Diseases and Beyond – | ||
6:30 – 7:20 | Breakfast and Registration | |
Meet the Course Director Workshop (optional): | ||
7:20 – 7:30 | Announcements | |
7:30 – 8:10 | Diagnosis of Aquaporin-4-IgG Positive Neuromyelitis Optica Spectrum Disorders | |
7:55 – 8:05 | Cases in AQP4+NMOSD | |
8:05 – 8:10 | Questions | |
8:10 – 8:50 | Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease | |
8:35 – 8:45 | Cases in MOGAD | |
8:45 – 8:50 | Questions | |
8:50 – 9:30 | Acute & Maintenance Treatment of AQP4+NMOSD and MOGAD | |
| 9:15 – 9:25 | Cases in Treatment of AQP4+NMOSD and MOGAD |
| 9:25 – 9:30 | Questions |
9:30 – 9:40 | Break | |
9:40 – 10:20 | Myelopathy Differential Diagnosis | |
10:05 – 10:15 | Myelopathy Cases | |
10:15 – 10:20 | Questions | |
10:20 – 11:00 | Neurosarcoidosis and Neuro-Rheumatology | |
10:45 – 10:55 | Cases in Neurosarcoidosis and Rheumatology | |
10:55 – 11:00 | Questions | |
11:00 – 11:10 | Break | |
11:10 – 11:50 | Neuro-Ophthalmology in Autoimmune Neurology | |
11:35 – 11:45 | Case Discussions in Neuro-Ophthalmology | |
11:45 – 11:50 | Questions | |
11:50 – 12:30 | Differential Diagnosis of Neuro-Ophthalmologic Presentations | |
12:15 – 12:25 | Cases in Neuro-Ophthalmology Differential | |
12:25 – 12:30 | Questions | |
Wednesday, February 3, 2027 | ||
Multiple Sclerosis Management – Moderated by Samantha Banks, M.D. | ||
6:30 – 7:20 | Breakfast and Registration | |
Meet the Course Director Workshop (optional): | ||
7:20 – 7:30 | Announcements | |
7:30 – 8:10 | Treatment Approach and Drug Selection in Relapsing Forms of MS | |
7:55 – 8:05 | Case Discussions in MS Treatment | |
8:05 – 8:10 | Questions | |
8:10 – 8:50 | DMTs in Progressive MS and Discontinuation | |
8:35 – 8:45 | Cases in Progressive MS and Discontinuation | |
8:45 – 8:50 | Questions | |
8:50 – 9:05 | Break | |
9:05 – 9:45 | DMT Mechanisms of Action and Side Effects Prevention and Management Of | |
9:30 – 9:40 | Cases in DMT Side Effects | |
9:40 – 9:45 | Questions | |
9:45 – 10:25 | CNS Infection in Immunocompromised Patients | |
10:10 – 10:20 | Cases in Infectious Complications | |
10:20 – 10:25 | Questions | |
10:25 – 10:40 | Break | |
10:40 – 11:20 | Changes Across the Lifespan in Women with MS | |
11:05 – 11:10 | Cases in Conception, Pregnancy, Breast Feeding, and Menopause | |
11:10 – 11:15 | Questions | |
11:20 – 12:00 | Treatment of Fatigue and Cognitive Impairment in MS | |
11:45 – 11:55 | Cases in MS Symptom Management | |
11:55 – 12:00 | Questions | |
12:00 – 12:45 | Poster Session | |
Thursday, February 4, 2027 | ||
Autoimmune & Paraneoplastic Encephalitis & Its Spectrum - | ||
6:30 – 7:20 | Breakfast and Registration | |
Meet the Course Director Workshop (optional): | ||
7:20 – 7:30 | Announcements | |
7:30 – 8:10 | Treatment-Responsive Rapidly Progressive Dementia: Causes, Cases and How to Find Them | |
7:55 – 8:05 | Case Discussions in RPD | |
8:05 – 8:10 | Questions | |
8:10 – 8:50 | Antibodies to Cell-Surface/Synaptic Targets: How Clinical Clues Drive Pathogenic Observations | |
8:35 – 8:45 | Case Discussions | |
8:45 – 8:50 | Questions | |
8:50 – 9:30 | Ordering and Interpreting of Neural Antibodies | |
9:30 – 9:40 | Case Discussions | |
9:40 – 9:45 | Questions | |
9:30 – 9:40 | Break | |
9:40 – 10:20 | Autoimmune Encephalitis Diagnosis and Misdiagnosis | |
10:10 – 10:20 | Autoimmune Encephalitis Cases | |
10:20 – 10:25 | Questions | |
10:20 – 11:00 | Autoimmune Movement Disorders & Stiff Person Spectrum Disorders | |
11:05 – 11:10 | Cases in Autoimmune Movement Disorders | |
11:10 – 11:15 | Questions | |
11:00 – 11:10 | Break | |
11:10 – 11:50 | Advances and Complications of CAR T-Cell Therapy and Immune Checkpoint Inhibitors | |
11:35 – 11:45 | Cases in CAR-T and ICI | |
11:45 – 11:50 | Questions | |
11:50 – 12:30 | Autoimmune/Paraneoplastic Cases in the PNS: An Update | |
12:15 – 12:25 | Autoimmune PNS Cases | |
12:25 – 12:30 | Questions | |
12:30 – 12:40 | Thank You and Closing Remarks | |
Lodging
Rooms have been reserved for attendees and their guests at The Westin Hapuna Beach Resort for discounted rates starting at $380/night. To make reservations please use this link.
All travel and lodging expenses are the sole responsibility of the individual registrant.
Mark Keegan, M.D.
Eoin Flanagan, M.B., B.Ch.
Samantha Banks, M.D.
Sarosh Irani, B.M., B.Ch., D.Phil.
Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
Credit Statements:
AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 17.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
AAPA
Mayo Clinic College of Medicine and Science has been authorized by the American Academy of Physician Associates (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 17.00 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
ACHE
By attending the Multiple Sclerosis and Autoimmune Neurology Update 2027 offered by Mayo Clinic College of Medicine and Science participants may earn up to 17.00 ACHE Qualifying Education Hours toward initial certification or recertification of the Fellow of the American College of Healthcare Executives (FACHE) designation.
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 17.00 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
ICPE
This activity was planned by and for the healthcare team, and learners will receive 17.00 Interprofessional Continuing Education (IPCE) credit for learning and change.
Other Healthcare Professionals:
A record of attendance will be provided to all registrants for requesting credits in accordance with state nursing boards, specialty societies or other professional associations.
| Credit Breakdown | |
|---|---|
| Monday | 4.00 |
| Tuesday | 4.50 |
| Wednesday | 4.00 |
| Thursday | 4.50 |
| Total | 17.00 |
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Available Credit
- 17.00 AAPA Category 1
- 17.00 ACHE
- 17.00 AMA PRA Category 1 Credit™
- 17.00 ANCC
- 17.00 Attendance
- 17.00 IPCE
Thank you for your interest in Multiple Sclerosis and Autoimmune Neurology Update 2027. This course is currently in the early planning stages. If you’d like to be notified when opportunities become available, please add your name to our Notify Me list. Signing up to be notified will ensure that you receive an email when exhibitor information is available. No additional information is available until then.
To see the course fee, please log in or create an account
| Registration Fee(s) | |
|---|---|
| M.D., D.O., Ph.D. | $1195 |
| Allied Health, NP, PA, Retirees | $975 |
Before registering, please update your profile.
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Every effort will be made to accommodate dietary requirements; however, some requests may not be feasible based on venue kitchen capabilities. Attendees will be contacted in advance if a dietary restriction cannot be fulfilled.
The Mayo Clinic School of Continuous Professional Development strives for fully accessible learning experiences. If you anticipate any barriers while attending this course, please reach out to the course coordinator who will be in touch with all registrants. If you need disability-related accommodations, please contact the Office of Wellness and Academic Support – Disability Access Services at MCCMS.DS@mayo.edu.
Cancellation and Refund Policy
View Cancellation and Refund Policy
All requests must be submitted in writing using the Contact Us Form.
Any use of this site constitutes your agreement to the Terms and Conditions of Registration.

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