Mayo Clinic Talks COVID-19 Miniseries Episode 10: How to Mitigate Drug-Induced Sudden Cardiac Death From Hydroxychloroquine

Mayo Clinic Talks

Mayo Clinic Talks Podcast #143

COVID-19 Miniseries Episode 10: How to Mitigate Drug-Induced Sudden Cardiac Death From Hydroxychloroquine

Registration required for CME credit


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COVID-19 information evolves daily.  The views and perspectives shared in these resources are presented based on information available at the time of recording.
Recorded March, 2020

For the most up to date information visit:

CDC - Information for Healthcare Professionals about Coronavirus (COVID-19)
World Health Organization's Country & Technical Guidance - Coronavirus disease (COVID-19)
AskMayoExpert COVID-19 Navigator
COVID-19 Online Education, Resources and Updates

Guest: Michael J. Ackerman, M.D., Ph.D. 
Host: Amit K. Ghosh, M.D., M.B.A.

The administration of hydroxychloroquine and azithromycin, along with other very common medications could result in drug-induced sudden cardiac death caused by drug-induced QT prolongation, in some patients. In order to avoid the wrong medication, for the wrong patient, at the wrong time, Dr. Michael Ackerman shares how to assess your patient’s risk, how to find and measure their QTc value, and neutralize the threat.

Deeper Dive:

Link to Journal Pre-Proof:
Giudicessi JR, Noseworthy PA, Friedman PA, Ackerman MJ. Urgent guidance for navigating and circumventing the QTc prolonging and torsadogenic potential of possible pharmacotherapies for COVID-19 [published online ahead of print March 25, 2020]. Mayo Clin Proc.

Mayo Clinic Connected Care - Genetic Heart Rhythm Diseases



Target Audience

This course is intended for primary care providers: physicians, nurse practitioners, and physician assistants

Learning Objectives

Upon completion of the Mayo Clinic Talks Podcast episode, learners should be able to:

  • Recall common medications that can cause QT prolongation
  • Recall the risk factors that can prolong QT interval
  • Recall the eyeball test for QTc
  • Determine the risk stratification for prolonged QT interval

Participation in this Mayo Clinic online course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course.

Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit
  • 0.50 Attendance
Course opens: 
Course expires: 

Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Credit Statement(s):


Mayo Clinic College of Medicine and Science designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s), please go here to review disclosures.

Available Credit

  • 0.50 AMA PRA Category 1 Credit
  • 0.50 Attendance


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