Mayo Clinic Talks COVID-19 Miniseries Episode 34: Multisystem Inflammatory Syndrome (MIS-C) in Pediatric Patients
COVID-19 information evolves daily. The views and perspectives shared in these resources are presented based on information available at the time of recording.
Nipunie S. Rajapakse, M.D., M.P.H.
Amit K. Ghosh, M.D.
Patients under 21 who present with fever, lab evidence of inflammation, multisystem involvement, and recent or current SARS-CoV-2 infection fall under the case definition for multisystem inflammatory syndrome. They commonly present with persistent fever and gastrointestinal symptoms and concerningly, shock. Why are we seeing disproportionate rates in children of racial and ethnic minorities? Dr. Nipunie Rajapaske concisely covers what’s known about this syndrome and the data supporting its emergence as a post-infection complication.
CDC Health Advisory on Multisystem Inflammatory Syndrome in Children (MIS-C)
An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study
This course is intended for primary care providers: physicians, nurse practitioners, and physician assistants
Upon completion of the Mayo Clinic Talks Podcast episode, learners should be able to:
- Recall laboratory markers of inflammation and their role in diagnosis of multisystem inflammatory syndrome
- Recall the case definition of multisystem inflammatory disease and how it differs from Kawasaki disease and Toxic Shock Syndrome
- Recall the disproportionate prevalence of multisystem inflammatory disease in children of racial and ethnic minorities
- Recall the data supporting multisystem inflammatory disease being a post-infection complication rather than a direct viral injury
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