Mayo Clinic Talks COVID-19 Miniseries Episode 57: Transcending the Valley of Death - COVID-19 mRNA Vaccine Update

Mayo Clinic Talks

Mayo Clinic Talks Podcast #209

COVID-19 Miniseries Episode 57: Transcending the Valley of Death - COVID-19 mRNA Vaccine Update

Registration required for CME credit


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COVID-19 information evolves daily.  The views and perspectives shared in these resources are presented based on information available at the time of recording.
Recorded December, 2020

For the most up to date information visit:
CDC - Information for Healthcare Professionals about Coronavirus (COVID-19)
World Health Organization's Country & Technical Guidance - Coronavirus disease (COVID-19)
AskMayoExpert COVID-19 Navigator
COVID-19 Online Education, Resources and Updates

Guest: Gregory A. Poland, M.D.
Host: Amit K. Ghosh, M.D.


It is projected that by March of 2021, 1:700 Americans will have died of COVID-19. The historic pace of COVID-19 vaccine development was made possible by the countless sacrifices of many individuals across healthcare, research, health and human services, the Department of Defense, and other key sectors. This interprofessional collaboration required many to set life aside and work tirelessly to bring an effective vaccine to market, quickly. While mRNA vaccines have been in development since the 1990s, the COVID-19 vaccine efficacy rate of 95-100% across studied ages, race and ethnicities, and comorbidities is unprecedented. The questions left to answer are, how long will the efficacy last? In larger population studies, what is the safety/allergy/hypersensitivity profile? What impact does the vaccine have on asymptomatic carrier spread? Who shouldn’t get the vaccine? Dr. Greg Poland breaks down everything you need to know about the mRNA COVID-19 vaccines. 

Additional Resources:
Connect with the Mayo Clinic’s School of Continuous Professional Development online at or on Twitter @MayoMedEd


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This course is intended for primary care providers: physicians, nurse practitioners, and physician assistants

Learning Objectives

Upon completion of the Mayo Clinic Talks Podcast course, learners should be able to:

  • Describe the current treatment recommendations for patients with hyperlipidemia.
  • List the various categories of hypertension.
  • Describe the current pharmacologic treatment available for patients with osteoporosis.

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Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit
  • 0.50 Attendance
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In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

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Mayo Clinic College of Medicine and Science designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s), please go here to review disclosures.

Available Credit

  • 0.50 AMA PRA Category 1 Credit
  • 0.50 Attendance


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