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Mayo Clinic Talks COVID-19 Miniseries Episode 69: Post-Acute COVID-19 and Central Sensitization

Mayo Clinic Talks

Mayo Clinic Talks Podcast

Episode 229: COVID-19 Miniseries Episode 69: Post-Acute COVID-19 and Central Sensitization

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COVID-19 information evolves daily.  The views and perspectives shared in these resources are presented based on information available at the time of recording.
Recorded March, 2021.

For the most up to date information visit:
CDC - Information for Healthcare Professionals about Coronavirus (COVID-19)
World Health Organization's Country & Technical Guidance - Coronavirus disease (COVID-19)
AskMayoExpert COVID-19 Navigator
COVID-19 Online Education, Resources and Updates

Guest: Elizabeth C. Wight, M.D.
 
Host: Amit K. Ghosh, M.D.
@AmitGhosh006

 

Central sensitization (CS) describes pathophysiologic changes in the central nervous system, including alterations in neurochemistry, CNS receptors, endogenous opioid system hyperactivity, cytokine and HPA axis dysregulation, and sympathetic hyperactivity. Collectively, these changes result in amplification of pain and sensory signals, leading to widespread pain, fatigue and other sensory sensitivities. Fibromyalgia and Chronic Fatigue Syndrome are established diagnoses/manifestations of central sensitization. In the era of the COVID-19 pandemic, we continue to learn about Post-Acute COVID-19 Syndrome, a manifestation of central sensitization similar to other post-infectious forms of CS, which underlies the persistent symptoms that many people experience after initial recovery from COVID-19. Elizabeth C. Wight, M.D. joins us to talk about Mayo Clinic’s treatment approach to central sensitization, which is rooted in empowering patients with education and a framework for a self-management program. This includes stress management, moderation, positive thinking, decreasing focus on symptoms, sleep hygiene, and Cognitive Behavioral Therapy among others.

Additional resources: 
•    Post-COVID Recovery on Mayo Clinic Connect: https://connect.mayoclinic.org/blog/post-covid-recovery/ 
•    Mayo Clinic’s “A Systematic Approach to Medically Unexplained Symptoms 2021” course can be found at https://ce.mayo.edu/internal-medicine/content/systematic-approach-medically-unexplained-symptoms-2021#group-tabs-node-course-default1 
•    Clauw DJ. Fibromyalgia: A clinical review. JAMA. 2014;311(15):1547-1555. doi:10.1001/jama.2014.3266
•    Clauw DJ. Fibromyalgia and related conditions. Mayo Clin Proc. 2015 May;90(5):680-92. https://doi.org/10.1016/j.mayocp.2015.03.014 
•    Harte, SE, Harris, RE, Clauw, DJ. The neurobiology of central sensitization. J Appl Behav Res. 2018; 23(2): e12137. https://doi.org/10.1111/jabr.12137 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd

 

Target Audience

This course is intended for primary care providers: physicians, nurse practitioners, and physician assistants

Learning Objectives

Upon completion of the Mayo Clinic Talks Podcast course, learners should be able to:

  • Describe the current treatment recommendations for patients with hyperlipidemia.
  • List the various categories of hypertension.
  • Describe the current pharmacologic treatment available for patients with osteoporosis.

Participation in this Mayo Clinic online course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in this course.

Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit
  • 0.50 Attendance
Course opens: 
04/08/2021
Course expires: 
12/29/2022
Cost:
$10.00

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In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

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AMA

Mayo Clinic College of Medicine and Science designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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Available Credit

  • 0.50 AMA PRA Category 1 Credit
  • 0.50 Attendance

Price

Cost:
$10.00
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