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ForwardA Systematic Approach to Medically Unexplained Symptoms 2026
This course offers Live (in-person) and Livestream (virtual) attendance options
Course Directors - Michael R. Mueller, MD, and Elizabeth C. Wight, MD
August 5 - 8, 2026 - Loews Coronado Bay Resort - Coronado, California
All scheduled times are in the Pacific Time Zone
This course offers evidence-based strategies for managing medically unexplained conditions. Review of the pathophysiological process of nociplastic pain will be followed by symptom-specific didactic sessions, case vignettes, clinical pearls, Q&A sessions, daily roundtable discussions and group problem-solving exercises. An optional session on practical communication strategies will be offered in-person.
*To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery and post-course recordings will not be available. Livestream will be presented as voiceover PowerPoint only, with no live camera feed on the presenter.
| Registration Fees | |
|---|---|
| General Session | |
| MD, DO, PhD | $995 |
| Nurse Practitioner, Physician Assistant, Nurse, Resident, Fellow, Allied Health Professional, Retiree | $925 |
| Communicate with Confidence Workshop - Optional, separate purchase required, no livestream, in-person only | $150 |
Target Audience
This course is intended for general internists, internal medicine subspecialists, family medicine physicians, physician assistants, nurse practitioners, and other primary healthcare professionals who practice in or have a special interest in treating medically complex patients.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Differentiate between nociceptive, neuropathic, and nociplastic pain mechanisms
- Evaluate postural orthostatic tachycardia syndrome
- Critique common patient-reported etiologies using current evidence bases to provide empathetic and scientifically accurate counseling
- Apply practical nonpharmacologic strategies for management of chronic pain, fatigue, orthostatic intolerance, and brain fog
- Identify treatment strategies for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
A Systematic Approach to Medically Unexplained Symptoms 2026 |
Loews Coronado Bay Resort – Coronado, CA |
Printable Programs General Session Communicate with Confidence Workshop *The workshop is optional attendance, separate registration, and offered in-person ONLY |
Times are listed in the Pacific Time Zone |
WEDNESDAY, AUGUST 5, 2026 – General Session
7:00 – 7:30 PM | Breakfast and Registration |
7:30 – 7:50 AM | Introduction and Brief Pathophysiologic Overview of Medically Unexplained Symptoms |
7:50 – 8:25 AM 8:25 - 8:35 AM | Fibromyalgia |
8:35 – 9:15 AM 9:15 - 9:25 AM | Biofeedback and Wearable Devices |
9:25 – 10:00 AM 10:00 - 10:10 AM | Approach to Breast Pain |
10:10 – 10:40 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
10:40 – 11:25 AM 11:25 - 11:35 AM | Approach to Chronic Headaches |
11:35 AM – 12:20 PM 12:20 - 12:30 PM | Evaluation of Thyroid Hormones: Myths, Truths, and In-Between |
12:30 – 12:45 PM | Rapid Fire Case |
| 12:45 PM | ADJOURN – Have a great afternoon! |
WEDNESDAY, AUGUST 5, 2026 – Communicate with Confidence Workshop
12:45 – 1:15 PM | Lunch for Workshop Attendees |
1:15 – 2:00 PM | Discussion of Complex Cases, Pre-Test |
2:00 – 2:30 PM | Group Case Exercise |
2:30 – 3:00 PM | Role Playing Case Exercise |
3:00 – 3:15 PM | Large Group Discussion, Post-Test |
3:15 PM | ADJOURN - Have a great afternoon! |
THURSDAY, AUGUST 6, 2026 – General Session
7:00 – 7:30 AM | Breakfast with the Experts Roundtable chats with previous day speakers to answer additional questions by the learners. Learners are welcome to bring food/beverage into the breakout room. Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
7:30 – 8:15 AM 8:15 - 8:25 AM | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome |
8:25 – 9:10 AM | Chronic Dizziness: A New Approach to an Old Problem |
9:20 – 10:00 AM | Approach to Insomnia |
10:10 – 10:40 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
10:40 – 11:25 AM | Chest Pain and Palpitations Michael W. Cullen. MD Q&A |
11:35 AM – 12:20 PM | Postural Tachycardia Syndrome |
12:30 – 12:45 PM | Rapid Fire Case Course Director Group exercise to discuss a specific case related to the talks of the day. |
12:45 PM | ADJOURN – Have a great afternoon! |
FRIDAY, AUGUST 7, 2026 – General Session
7:00 – 7:30 AM | Breakfast with the Experts Roundtable chats with previous day speakers to answer additional questions by the learners. Learners are welcome to bring food/beverage into the breakout room. Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
7:30 – 8:15 AM 8:15 - 8:25 AM | Hypermobile Ehlers Danlos and Hypermobility Syndromes |
8:25 – 9:10 AM | Approach to Chronic Gastrointestinal Symptoms |
9:20 – 9:50 AM | Understanding Low Cortisol and Adrenal Fatigue: Clinical Insights for Primary Care |
10:00 – 10:30 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
10:30 – 11:15 AM | Importance of Patient Stories and Medically Unexplained Symptoms |
11:25 – 11:55 M 11:55 AM – 12:05 PM | A Practical Approach to Pruritus of Unknown Origin |
12:05 – 12:35 PM 12:35 – 12:45 PM | The Dreaded Disability Form |
12:45 – 1:00 PM | Rapid Fire Case Course Director Group exercise to discuss a specific case related to the talks of the day. |
1:00 PM | ADJOURN – Have a great afternoon! |
SATURDAY, AUGUST 8, 2026 – General Session
7:00 – 7:30 AM | Breakfast with the Experts Roundtable chats with previous day speakers to answer additional questions by the learners. Learners are welcome to bring food/beverage into the breakout room. Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
7:30 – 8:15 AM 8:15 - 8:25 AM | Psychiatric and Functional Disorders in General Medical Practice |
8:25 – 9:10 AM | Approach to Pelvic Pain and Dysfunction Isabel C. Green, MD, MHPE Q&A |
9:20 – 10:05 AM | Hormone Supplementation Do's and Don'ts |
10:15 – 10:45 AM | Break with the Experts Livestream audience will access Breakout rooms within Zoom to connect with speakers. |
10:45– 11:35 AM 11:35 - 11:45 AM | Physician Burnout / Taking Care of Ourselves Greg P. Couser, MD, MPH Q&A |
11:45 AM – 12:15 PM | Cross-Cultural Communication Video |
12:15 – 12:30 PM | Rapid Fire Case Course Director Group exercise to discuss a specific case related to the talks of the day. |
12:30 PM | ADJOURN – Thank you for attending Medically Unexplained Symptoms 2026! |
Guest rooms have been reserved for attendees and their guests with special course rates at the Loews Coronado Bay Resort. To receive the special rate, reservations must be made before the room block is filled or before the expiration date of Monday, July 13, 2026, whichever comes first. Reservations will be made following this date based on space and availability rate. The room block is expected to fill, register for the conference and reserve your room early.
Reservations:
Online Booking: Mayo Clinic Booking Link
Phone Booking: 1-800-815-6397 - Reference the group name when booking your reservation "Mayo Clinic 2026 conference.”
Room Rate: Run of House- $289.00 per night (plus tax).
Check in: 4:00 pm, PT; Check Out: 11:00 am, PT
Note: Waived resort fee ($39.00 per room, per day)- amenities included, but not limited to:
- Fitness center and studio access
- Daily group fitness classes
- Shuttle service to Silver Strand State Beach
- Shuttle service to Downtown Coronado Village
- High speed internet access for up to three devices
Parking and Transportation:
- Self-Parking: $47.00 per day maximum
- Valet Parking: $50.00 per day maximum
- Parking charges are subject to change without notice
Airport:
San Diego International Airport (SAN): 8 miles
All travel and lodging expenses are the sole responsibility of the individual registrant.
| Course Directors | ||
|---|---|---|
Michael R. Mueller, MD Elizabeth C. Wight, MD | ||
| Faculty | ||
Chris A. Aakre, MD | Amindra S. Arora, MB, BChir Professor of Medicine Division of Gastroenterology & Hepatology | Greg P. Couser, MD, MPH Assistant Professor of Psychiatry Assistant Professor of Medicine Division of Preventative, Occupational, and Aerospace Medicine |
| Michael W. Cullen, MD Associate Professor of Medicine Division of Cardiovascular Diseases | Daniel V. Dudenkov, MD Assistant Professor of Medicine Division of General Internal Medicine | Emrys Fonseca, MB, BCh, BAO, MS Psychiatrist Department of Psychiatry and Psychology |
| Shilpa N. Gajarawala, DMSc, MPAS, PA-C Assistant Professor of Obstetrics and Gynecology Division of General Internal Medicine | Stephanie L. Grach, MD, MS Assistant Professor of Medicine Division of General Internal Medicine | Isabel C. Green, MD Associate Professor of Obstetrics & Gynecology Department of Obstetrics & Gynecology |
| Mithri Junna, MD Assistant Professor of Neurology Department of Neurology | Jenny L. Link, MD Assistant Professor of Dermatology Department of Dermatology | Jean Marie McGowan, MD Instructor in Medicine Division of General Internal Medicine |
| Denise M. Millstine, MD Assistant Professor of Medicine Division of Women's Health Internal Medicine | LaSonya T. Natividad, ARNP, CNP, MSN** Instructor in Medicine Division of General Internal Medicine | Neena Natt, MD Associate Professor of Medicine Division of Endocrinology, Diabetes & Metabolism |
| Sandhya Pruthi, MD* Professor of Medicine Division of General Internal Medicine | Mabel Ryder, MD Associate Professor of Medicine Division of Endocrinology, Diabetes & Metabolism | Jeffrey P. Staab, MD, MS Professor of Psychology Department of Psychiatry & Psychology |
| Melanie D. Swift, MD, MPH Professor of Medicine Division of Preventive, Occupational and Aerospace Medicine | Elizabeth W. Westby, MD Assistant Professor of Family Medicine Department of Family Medicine | Nathan P. Young, DO Assistant Professor of Neurology Department of Neurology |
*Planning team member, AAFP diplomate
**Planning team member, ANCC diplomate
CME Program Manager- Deb Blomberg, MBA
CME Education Specialist- Sheila Terrill
RSTGIMCME@mayo.edu for questions or support
Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 24.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Credit allocation:
Wednesday 8/5/26 General Session: 5.25
Wednesday 8/5/26 Optional Workshop: 2.00
Thursday 8/6/26 General Session: 5.75
Friday 8/7/26 General Session: 6.00
Saturday 8/8/26 General Session: 5.50
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 24.50 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
MOC Statement
American Board of Internal Medicine (ABIM)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 24.50 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Other Healthcare Professionals:
A record of attendance will be provided to all registrants for requesting credits in accordance with state nursing boards, specialty societies or other professional associations.
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Available Credit
- 24.50 ABIM - Medical Knowledge
- 24.50 AMA PRA Category 1 Credit™
- 24.50 ANCC
- 24.50 Attendance
Before registering, please update your profile.
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Every effort will be made to accommodate dietary requirements; however, some requests may not be feasible based on venue kitchen capabilities. Attendees will be contacted in advance if a dietary restriction cannot be fulfilled.
The Mayo Clinic School of Continuous Professional Development strives for fully accessible learning experiences. If you anticipate any barriers while attending this course, please reach out to the course coordinator who will be in touch with all registrants. If you need disability-related accommodations, please contact the Office of Wellness and Academic Support – Disability Access Services at MCCMS.DS@mayo.edu.
Cancellation and Refund Policy
View Cancellation and Refund Policy
All requests must be submitted in writing using the Contact Us Form.
Any use of this site constitutes your agreement to the Terms and Conditions of Registration.