February 26 - 28, 2027 - Mayo Clinic - Kinne Auditorium - Jacksonville, Florida

This course offers Live (in-person) and Livestream (virtual) attendance options

This course covers advanced topics in neuro-oncology, offering a review of advances in diagnosis and treatment of individuals with nervous system tumors. The course covers highlights from including the latest advances in neurosurgery, radiation oncology, neurology, and medical oncology, discussing novel therapeutic approaches that are transforming clinical practice with personalized treatments.

General Session: April 29 - May 1, 2027 - JW Marriott Tucson Starr Pass Resort & Spa - Tucson, Arizona

Special Feature: Pediatric Palliative Cases (Pre-Course Session Day) April 28, 2027. This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic's Updates in Palliative Care is a multidisciplinary CME course designed to build and enhance your palliative care knowledge. Experts from Mayo Clinic provide clinically relevant pearls for palliative care providers and clinicians from primary care, hematology/oncology, hospital medicine, critical care, pediatrics, and related specialties. If you care for patients with serious illness and are looking to broaden your skills beyond the basics, this is the course for you.

September 18-19, 2026 - Assisi Heights - Rochester, Minnesota

This course is offered Live (in-person) only

The Mayo Osteopathic Research and Education Conference is a regional conference with an emphasis on osteopathic manual treatment and osteopathic research. It is a hub for networking and recruiting for osteopathic residents and physicians in the upper Midwest. Its focus is hands-on osteopathic education for residents and physicians.

April 8 - 10, 2027 - Integrated Education and Research Building - Phoenix, Arizona

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic Healthy Longevity Medicine is a comprehensive CME course designed to provide clinicians with clinically relevant knowledge in the emerging discipline of longevity medicine. The course delivers a structured curriculum focused on applying aging biology to patient care, with an emphasis on prevention, early risk detection, and healthspan extension. Participants will examine key biological mechanisms of aging—the hallmarks of aging—and explore how these processes contribute to functional decline, chronic disease risk, and potential targets for clinical intervention. The course covers a wide range of topics, including biomarkers of aging (biological age clocks), multidimensional assessment in geromedicine, lifestyle interventions, and emerging pharmacologic and regenerative therapies. Led by faculty from Mayo Clinic, alongside invited experts from national and international academic institutions, the course features a blend of didactic lectures and interactive case-based discussions. The course places emphasis on the critical appraisal of translational and clinical trials and the ethical considerations unique to the practice of geromedicine. Upon completion, participants will be equipped to thoughtfully integrate principles of geromedicine into their clinical care and contribute to the responsible advancement of longevity medicine.

February 22 - 26, 2027 - Grand Hyatt Kauai Resort & Spa - Koloa, Hawaii

This course offers Live (in-person) and Livestream (virtual) attendance options

Mayo Clinic Psychiatry’s flagship course, Psychiatry Clinical Updates, delivers practical, clinically focused guidance for managing psychiatric conditions across the lifespan. This year’s program highlights key updates in child, adolescent, adult, and geriatric psychiatry, with sessions covering mood disorders, ADHD, and reproductive psychiatry. The course also features focused updates on evidence-based psychotherapies and new, evolving pharmacologic treatment options.

July 17 - 18, 2026 - Radisson Blu Mall of America - Bloomington, Minnesota

This course offers Live (in-person) and Livestream (virtual) attendance options

This inaugural course bridges a critical knowledge gap by delivering comprehensive, evidence-based education on managing patients with substance use disorders. Designed for physicians, residents, fellows, and advanced practice providers across diverse specialties and clinical settings—ranging from inpatient to outpatient, virtual to in-person, and rural to urban—it equips non-addiction specialists with practical skills and strategies to provide effective, compassionate care.