46th Annual Practice of Internal Medicine
This course offers Live (in-person) and Livestream (virtual) attendance options

Course Directors: Brandon P. Verdoorn, M.D., and Hannah C. Nordhues, M.D.
May 11 - 15, 2026 - Hilton Rochester Mayo Clinic Area - Rochester, Minnesota
Practice of Internal Medicine is a postgraduate course offering internists and primary care professionals a state-of-the-art update. Mayo Clinic faculty present lectures on common clinical problems across gastroenterology, infectious diseases, rheumatology, geriatrics, emergency medicine, cardiology, neurology, endocrinology, pulmonary, and women’s health.
To see the course fee, please log in or create an account
| Registration Fee(s) | |
|---|---|
| M.D., D.O., Ph.D. | $950 |
| Allied Health, NP, PA, Retirees | $900 |
Target Audience
This course is designed for general internists, internal medicine subspecialists, family medicine physicians, and other primary healthcare professionals.
Learning Objectives
Upon completion of this activity, participants should be able to:
- Describe the current approach to diagnosis and treatment of MASLD.
- Outline treatment options for Alzheimer’s Disease in 2026.
- Advise patients on breast cancer screening, balancing risks and benefits and incorporating society guidelines.
Attendance at any Mayo Clinic course does not indicate or guarantee competence or proficiency in the skills, knowledge or performance of any care or procedure(s) which may be discussed or taught in this course.
Monday, May 11, 2026 | |
6:45 a.m. | Registration & Breakfast |
7:45 a.m.
| Welcome and Course Overview |
8:00 a.m.
| The Eye in Primary Care |
8:35 a.m.
| The Ups and Downs of Recurrent Emesis: Cyclical Vomiting Syndrome and Cannabis Hyperemesis |
9:10 a.m.
| All About GLP-1’s: Indications, Side Effects, and Benefits |
9:45 a.m. | Break |
10:05 a.m.
| Is This Hard on My Kidneys? |
10:40 a.m.
| Cases in COPD |
11:15 a.m.
| Clinical Pearls – Gastroenterology |
11:55 a.m. | Lunch Break |
1:00 p.m.
| Depression in Primary Care: Diagnosis and Management Options |
1:35 p.m.
| Medical Cannabis and CBD Products in Older Adults |
2:10 p.m. | Break |
2:30 p.m.
| Nocturnal Leg Cramps: Management for the Generalist |
3:05 p.m.
| Cases in HFpEF and GDM Therapy |
3:40 p.m. | Monday Highlights |
3:45 p.m. | Adjourn |
Tuesday, May 12, 2026 | |
7:00 a.m. | Breakfast |
7:55 a.m.
| Daily Overview |
8:00 a.m.
| Breast Disease and Screening in 2026 |
8:35 a.m.
| Chest Pain and Palpitations |
9:10 a.m.
| Memory Problems: What to Ask, When to Worry, and What to Do |
9:45 a.m. | Break |
10:05 a.m.
| Practice Changing Updates in Primary Care |
10:40 a.m.
| Primary Care for Solid Organ Transplant Recipients |
11:15 a.m.
| Clinical Pearls - General Internal Medicine |
11:55 a.m. | Lunch Break |
1:00 p.m.
| Rheumatology Curbside Consults |
1:35 p.m.
| Hypercalcemia: Diagnosis, Management, and Pitfalls in Primary Care |
2:10 p.m. | Break |
2:30 p.m.
| Cases in VTE, from Simple to Complex |
3:05 p.m.
| Cases from the Women’s Health Clinic |
3:40 p.m. | Tuesday Highlights |
3:45 p.m. | Adjourn |
Wednesday, May 13, 2026 | |
7:00 a.m. | Breakfast |
7:55 a.m.
| Daily Overview |
8:00 a.m.
| Sports Medicine for the Generalist |
8:35 a.m.
| Diagnosis and Treatment of MASLD in Primary Care |
9:10 a.m.
| Quick Office CBT for Uncertain Times |
9:45 a.m. | Break |
10:05 a.m.
| Adrenal Insufficiency – What PCPs Need to Know |
10:40 a.m.
| Clinical Pearls – Neurology |
11:15 a.m.
| Clinical Pearls – Addiction Medicine |
11:55 a.m. | Lunch Break |
1:00 p.m.
| Updates on Multiple Sclerosis Diagnosis and Management |
1:35 p.m.
| Radiation Therapy for Benign Conditions: What’s New |
2:10 p.m. | Break |
2:30 p.m.
| Common Cosmetic Dermatology Concerns for the Internist |
3:05 p.m.
| Chest Pain and Palpitations |
3:40 p.m. | Wednesday Highlights |
3:45 p.m. | Adjourn |
Thursday, May 14, 2026 | |
7:00 a.m. | Breakfast |
7:55 a.m.
| Daily Overview |
8:00 a.m.
| Myalgic Encephalomyelitis/Chronic Fatigue Syndrome |
8:35 a.m.
| Approach to Insomnia |
9:10 a.m.
| Updates on Personal Health Devices and Apps Patients Use |
9:45 a.m. | Break |
10:05 a.m.
| Hereditary Cancer Syndromes |
10:40 a.m.
| Primary Care of the BMT Patient |
11:15 a.m.
| MGUS and Dysproteinemias |
11:55 a.m. | Lunch Break |
1:00 p.m.
| Primary Care of the Patient with Advanced CKD |
1:35 p.m.
| Updates in Cervical Cancer Screening: Primary HPV, Self-Collection, and More |
2:10 p.m. | Break |
2:30 p.m.
| Updates in Alzheimer’s Disease Treatment – Where Are We in 2026 |
3:05 p.m.
| Approach to Breast Pain |
3:40 p.m. | Wednesday Highlights |
3:45 p.m. | Adjourn |
Friday, May 15, 2026 | |
7:00 a.m. | Breakfast |
7:55 a.m.
| Daily Overview |
8:00 a.m.
| Approach to Falls in Older Adults |
8:35 a.m.
| Management of Common Painful Spine Conditions: Neck Pain, Back Pain, Radiculopathy |
9:10 a.m.
| An Update on H. Pylori: Diagnosis and Management |
9:45 a.m. | Break |
10:05 a.m.
| Controversies in Advance Care Planning: Can We Just Stop Doing ACP Now? |
10:40 a.m.
| Systemic Lupus Erythematosus |
11:15 a.m.
| Pharmacotherapy for Alcohol Use Disorder |
11:50 a.m.
| Wrap-Up and Closing Remarks |
12:00 p.m. | Adjourn |
All travel and lodging expenses are the sole responsibility of the individual registrant.
Accreditation Statement
In support of improving patient care, Mayo Clinic College of Medicine and Science is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
Credit Statement(s):
AMA
Mayo Clinic College of Medicine and Science designates this live activity for a maximum of 27.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
AAPA
Mayo Clinic College of Medicine and Science has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 27.75 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.
ANCC
Mayo Clinic College of Medicine and Science designates this activity for a maximum of 27.75 ANCC contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.
Other Healthcare Professionals:
A record of attendance will be provided to all registrants for requesting credits in accordance with state nursing boards, specialty societies or other professional associations.
| Day | Credit(s) |
|---|---|
| Monday | 6.00 |
| Tuesday | 6.00 |
| Wednesday | 6.00 |
| Thursday | 6.00 |
| Friday | 3.75 |
For disclosure information regarding Mayo Clinic School of Continuous Professional Development accreditation review committee member(s) and staff, please go here to review disclosures.
Available Credit
- 27.75 AAPA Category 1
- 27.75 AMA PRA Category 1 Credit™
- 27.75 ANCC
- 27.75 Attendance
Thank you for your interest in 46th Annual Practice of Internal Medicine. This course is currently in the early planning stages. If you’d like to be notified when opportunities become available, please add your name to our Notify Me list. Signing up to be notified will ensure that you receive an email when exhibitor information is available. No additional information is available until then.
To see the course fee, please log in or create an account
| Registration Fee(s) | |
|---|---|
| M.D., D.O., Ph.D. | $950 |
| Allied Health, NP, PA, Retirees | $900 |
Please update your profile to let us know if you have dietary restrictions or access requirements.
To claim credit for livestream participation in this course, learners must view the content during the hours posted for the live activity. This course is not approved for on-demand delivery.
Commitment to Belonging and Inclusion
Mayo Clinic School of Continuous Professional Development (MCSCPD) strives to foster a learning environment in which all individuals are valued, allowing all to achieve their fullest potential.
Cancellation and Refund Policy
View Cancellation and Refund Policy
All requests must be submitted in writing using the Contact Us Form.
Any use of this site constitutes your agreement to the Terms and Conditions of Registration.

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